A different perspective of elevated lactace in pediatric patients with diabetic ketoacidosis

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dc.authorid0000-0002-9809-0977en_US
dc.authorid0000-0002-2524-2124en_US
dc.authorid0000-0001-5137-0501en_US
dc.authorid0000-0002-5299-9480en_US
dc.contributor.authorÜnal, Edip
dc.contributor.authorPirinççioğlu, Ayfer Gözü
dc.contributor.authorYanmaz, Sercan Yücel
dc.contributor.authorYılmaz, Kamil
dc.contributor.authorTaşkesen, Mustafa
dc.contributor.authorHaspolat, Yusuf Kenan
dc.date.accessioned2021-11-30T13:20:30Z
dc.date.available2021-11-30T13:20:30Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractObjective: This study aims to determine the frequency and prognostic significance of lactic acidosis in children with diabetic ketoacidosis (DKA) admitted to the pediatric intensive care unit. Methods: The study was carried out retrospectively by examining the patients admitted to the pediatric intensive care unit for the treatment of DKA. The ages of the patients ranged from 2 to 18 years. The patients with the following parameters were enrolled in the study: serum blood glucose>200 mg/dL, ketonuria presence, venous blood gas pH ≤7.1, bicarbonate <15. Results: A total of 56 patients were included in the study with a mean age of 111.07 ± 51.13 months. The recovery time from DKA was 16.05 ± 6.25 h in the group with low lactate level and it was 13.57 ± 8.34 h in the group with high lactate level with no statistically significant difference. There was a negative correlation between lactate levels and the recovery time from DKA. Conclusion: Lactic acidosis is common in DKA, and unlike other conditions, such as sepsis, it is not always a finding of poor prognosis that predicts the severity of the disease or mortality. We think that high lactate may even protect against possible brain edema-cerebral damage in DKA.en_US
dc.identifier.citationÜnal, E., Pirinççioğlu, A. G., Yanmaz, S. Y., Yılmaz, K., Taşkesen, M., Haspolat, Y. K. ve diğerleri. (2020).A different perspective of elevated lactace in pediatric patients with diabetic ketoacidosis. Acta Endocrinologica (Bucharest), 16(1), 114-117.en_US
dc.identifier.doi10.4183/aeb.2020.114
dc.identifier.endpage117en_US
dc.identifier.issue1en_US
dc.identifier.pmid32685051
dc.identifier.scopus2-s2.0-85090643651
dc.identifier.scopusqualityN/A
dc.identifier.startpage114en_US
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/32685051/
dc.identifier.urihttps://hdl.handle.net/11468/8338
dc.identifier.volume16en_US
dc.identifier.wosWOS:000557583600021
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÜnal, Edip
dc.institutionauthorPirinççioğlu, Ayfer Gözü
dc.institutionauthorYanmaz, Sercan Yücel
dc.institutionauthorYılmaz, Kamil
dc.institutionauthorTaşkesen, Mustafa
dc.institutionauthorHaspolat, Yusuf Kenan
dc.language.isoenen_US
dc.publisherRomanian Academyen_US
dc.relation.ispartofActa Endocrinologica (Bucharest)
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBrain edemaen_US
dc.subjectChildrenen_US
dc.subjectDiabetic ketoacidosisen_US
dc.subjectIntensive careen_US
dc.subjectLactateen_US
dc.titleA different perspective of elevated lactace in pediatric patients with diabetic ketoacidosisen_US
dc.titleA different perspective of elevated lactace in pediatric patients with diabetic ketoacidosis
dc.typeArticleen_US

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