Impact of cigarette smoking on conversion from clinically isolated syndrome to clinically definite multiple sclerosis

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dc.contributor.authorArikanoglu, Adalet
dc.contributor.authorShugaiv, Erkingul
dc.contributor.authorTuzun, Erdern
dc.contributor.authorErakso, Mefkure
dc.date.accessioned2024-04-24T17:20:25Z
dc.date.available2024-04-24T17:20:25Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractMultiple sclerosis (MS) is known to be influenced by various environmental factors including cigarette smoking. To identify the impact of smoking on conversion from clinically isolated syndrome (CIS) to clinically definite MS (CDMS), 95 consecutive uniformly treated smoker (n = 31) and nonsmoker (n = 64) CIS patients were evaluated retrospectively. The smoker CIS patients did not differ from nonsmokers by means of demographic and clinical findings. In addition, there was no difference between the two groups with respect to rate and time of conversion to CDMS. However, white matter lesions were detected in magnetic resonance imagings (MRIs) of all smoking versus 54 of 64 (63.5%) nonsmoking CIS patients (p = 0.02). Our results show that smoking does not predict conversion from CIS to CDMS. However, smoking may be associated with the appearance of white matter lesions on MRI at CIS onset.en_US
dc.identifier.doi10.3109/00207454.2013.764498
dc.identifier.endpage479en_US
dc.identifier.issn0020-7454
dc.identifier.issn1563-5279
dc.identifier.issue7en_US
dc.identifier.pmid23302010
dc.identifier.scopus2-s2.0-84879180194
dc.identifier.scopusqualityQ2
dc.identifier.startpage476en_US
dc.identifier.urihttps://doi.org/10.3109/00207454.2013.764498
dc.identifier.urihttps://hdl.handle.net/11468/19037
dc.identifier.volume123en_US
dc.identifier.wosWOS:000321071600007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofInternational Journal of Neuroscience
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMultiple Sclerosisen_US
dc.subjectClinically Isolated Syndromeen_US
dc.subjectCigaretteen_US
dc.subjectSmokingen_US
dc.subjectWhite Matter Lesionsen_US
dc.titleImpact of cigarette smoking on conversion from clinically isolated syndrome to clinically definite multiple sclerosisen_US
dc.titleImpact of cigarette smoking on conversion from clinically isolated syndrome to clinically definite multiple sclerosis
dc.typeArticleen_US

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