Family patterns of psychopathology in psychiatric disorders

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dc.contributor.authorOzdemir, Osman
dc.contributor.authorBoysan, Murat
dc.contributor.authorOzdemir, Pinar Guzel
dc.contributor.authorCoskun, Salih
dc.contributor.authorOzcan, Halil
dc.contributor.authorYilmaz, Ekrem
dc.contributor.authorAtilla, Ercan
dc.date.accessioned2024-04-24T16:11:08Z
dc.date.available2024-04-24T16:11:08Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVE: Familial loading and crucial outcomes of family history of psychopathology in psychiatric disorders have long been recognized. There has been ample literature providing convincing evidence for the importance of family psychopathology in development of emotional disturbances in children as well as worse outcomes in the course of psychiatric disorders. More often, maternal psychopathology seems to have been an issue of interest rather than paternal psychopathology while effects of second-degree familiality have received almost no attention. In this study, we addressed the relations between affected first- and second-degree relatives of probands and categories of psychiatric disorders. METHOD: Subjects were 350 hospitalized psychiatric inpatients, consecutively admitted to psychiatry clinics in Van, Turkey. Mean age was 34.16 (SD +/- 12) and 51.4% of the sample consisted of male patients. Assessment of psychopathology in psychiatric probands was conducted based on DSM-IV TR. Familial loading of psychiatric disorders amongst first- and second-degree relatives of patients were initially noted primarily relying on patients' retrospective reports, and confirmed by both phone call and following official health records via the Medical Knowledge System. We analyzed the data using latent class analysis approach. RESULTS: We found four patterns of familial psychopathology. Latent homogeneous subsets of patients due to familial characteristics were as paternal kinship psychopathology with schizophrenia, paternal kinship psychopathology with mood disorders, maternal kinship psychopathology and core family psychopathology. CONCLUSION: Family patterns were critical to exerting variation in psychiatric disorders of probands and affected relatives. Probands with a core family pattern of psychopathology exhibited the most colorful clinical presentations in terms of variation in psychopathology. We observed a specificity of intergenerational transmission of psychiatric disorders when family patterns of psychopathology were taken into consideration, even second-degree relatives of psychiatric probands. Copyright (C) 2014 Elsevier Inc. All rights reserveden_US
dc.identifier.doi10.1016/j.comppsych.2014.09.014
dc.identifier.endpage174en_US
dc.identifier.issn0010-440X
dc.identifier.issn1532-8384
dc.identifier.pmid25308406
dc.identifier.scopus2-s2.0-84920864376
dc.identifier.scopusqualityQ1
dc.identifier.startpage161en_US
dc.identifier.urihttps://doi.org/10.1016/j.comppsych.2014.09.014
dc.identifier.urihttps://hdl.handle.net/11468/15282
dc.identifier.volume56en_US
dc.identifier.wosWOS:000353867100021
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofComprehensive Psychiatry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleFamily patterns of psychopathology in psychiatric disordersen_US
dc.titleFamily patterns of psychopathology in psychiatric disorders
dc.typeArticleen_US

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