The relationship between plasma atherogenic index and long-term outcomes after endovascular intervention in superficial femoral artery lesions

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dc.contributor.authorAltunova, Mehmet
dc.contributor.authorKarakayali, Muammer
dc.contributor.authorKarakan, Ceren Yildirim
dc.contributor.authorKarakurt, Seda Tukenmez
dc.contributor.authorDemirci, Gokhan
dc.contributor.authorAslan, Serkan
dc.contributor.authorGuler, Arda
dc.date.accessioned2024-04-24T17:14:45Z
dc.date.available2024-04-24T17:14:45Z
dc.date.issued2023
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives Peripheral arterial disease (PAD) results from the systemic atherosclerotic process. In this study, we aimed to determine the relationship between plasma atherogenic index (AIP), a ratio of molar concentrations of triglycerides to HDL-cholesterol, and long-term outcomes after endovascular therapy (EVT) in patients with superficial femoral artery (SFA) stenosis. Methods We retrospectively evaluated 673 patients who underwent EVT for PAD in our tertiary center between January 2015 and December 2020. In the receiver operating characteristic (ROC) curve analysis, the AIP value with the optimum cutoff value was determined as 0.576 to detect the presence of major adverse limb events (MALEs). Patients were divided into two groups according to low AIP (<0.576 as group 1) and high AIP (>0.576 as group 2). Results Among the major endpoints, long-term restenosis rates were significantly higher in patients in the high-AIP group than in the low-AIP group (p<.001). The lower extremity amputation rate was not statistically significant between the two groups. All-cause mortality rate (54 (31.6) versus 117 (68.4), p<.001) was significantly higher in patients in the high-AIP group than in the low-AIP group. In addition, the MALE rate (94 (29.2) versus 218 (62.1), p<.001) was significantly higher in patients in the high-AIP group than in those in the low-AIP group. Conclusions In conclusion, we found that AIP is a significant independent predictor of long-term MALE in patients who underwent EVT for SFA.en_US
dc.identifier.doi10.1177/17085381231193494
dc.identifier.issn1708-5381
dc.identifier.issn1708-539X
dc.identifier.pmid37540809
dc.identifier.scopus2-s2.0-85166917360
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1177/17085381231193494
dc.identifier.urihttps://hdl.handle.net/11468/18172
dc.identifier.wosWOS:001042375200001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofVascular
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPlasma Atherogenic Indexen_US
dc.subjectPeripheral Arterial Diseaseen_US
dc.subjectMajor Adverse Limb Eventsen_US
dc.titleThe relationship between plasma atherogenic index and long-term outcomes after endovascular intervention in superficial femoral artery lesionsen_US
dc.titleThe relationship between plasma atherogenic index and long-term outcomes after endovascular intervention in superficial femoral artery lesions
dc.typeArticleen_US

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