Inappropriate antimicrobial use in Turkish pediatric hospitals: A multicenter point prevalence survey

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dc.contributor.authorCeyhan, M.
dc.contributor.authorYildirim, I.
dc.contributor.authorEcevit, C.
dc.contributor.authorAydogan, A.
dc.contributor.authorOrnek, A.
dc.contributor.authorSalman, N.
dc.contributor.authorSomer, A.
dc.date.accessioned2024-04-24T16:14:53Z
dc.date.available2024-04-24T16:14:53Z
dc.date.issued2010
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives: Although well-defined principles of rational antimicrobial use are available, inappropriate prescribing patterns are reported worldwide. Accurate information on the usage of antimicrobials, including factors associated with and influencing their use, is valuable for improving the quality of prescription practices. Methods: In this cross-sectional point prevalence survey, data on patients hospitalized in 12 different children's hospitals were collected on a single day. Appropriateness of prescription was compared between the types of antimicrobials prescribed, indications, wards, and presence of/consultation with an infectious disease physician (IDP). Results: A total 711 of 1302 (54.6%) patients evaluated were receiving one or more antimicrobial drugs. The antimicrobial prescription rate was highest in pediatric intensive care (75.7%) and lowest in the surgery wards (37.0%). Of the 711 patients receiving antimicrobials, 332 patients (46.7%) were found to be receiving at least one inappropriately prescribed drug. Inappropriate use was most frequent in surgery wards (80.2%), while it was less common in oncology wards (31.8%; p < 0.001). Respiratory tract infection was the most common indication for antimicrobial use (29.4%). Inappropriate use was more common in deep-seated infections (54.7%) and respiratory infections (56.5%). Fluoroquinolones were used inappropriately more than any other drugs (81.8%, p = 0.021). Consultation with an IDP appears to increase appropriate antimicrobial use (p = 0.008). Conclusions: Inappropriate antimicrobial use remains a common problem in Turkish pediatric hospitals. Consultation with an IDP and prescribing antimicrobial drugs according to microbiological test results could decrease the inappropriate use of antimicrobials. (C) 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ijid.2009.03.013
dc.identifier.endpageE61en_US
dc.identifier.issn1201-9712
dc.identifier.issue1en_US
dc.identifier.pmid19487149
dc.identifier.scopus2-s2.0-74649086559
dc.identifier.scopusqualityQ1
dc.identifier.startpageE55en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijid.2009.03.013
dc.identifier.urihttps://hdl.handle.net/11468/15489
dc.identifier.volume14en_US
dc.identifier.wosWOS:000273987200009
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofInternational Journal of Infectious Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInappropriate Antimicrobial Usageen_US
dc.subjectPoint Prevalenceen_US
dc.subjectPediatric Hospitalsen_US
dc.titleInappropriate antimicrobial use in Turkish pediatric hospitals: A multicenter point prevalence surveyen_US
dc.titleInappropriate antimicrobial use in Turkish pediatric hospitals: A multicenter point prevalence survey
dc.typeArticleen_US

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