Conjunctival deposits as the first sign of systemic sarcoidosis in a pediatric patient
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Tarih
2006
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wichtig Editore
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
PURPOSE. Sarcoidosis is an inflammatory disease of unknown cause, characterized by noncaseating, granulomas. In this study, the authors present a sarcoidosis patient without systemic signs diagnosed by histopathologic analysis of conjunctival deposits. METHODS. A 10-year-old girl had bilateral, focal, multilobular, multiple pale yellow deposits in bulbar conjunctiva for a year. In the patient's biomicroscopic examination, numerous 0.50 to 2-mm diameter pale yellow deposits were determined in both bulbar conjunctivas. The patient had no other systemic or ocular complaints. A conjunctival biopsy was performed. RESULTS. The biopsy specimens showed noncaseating granulomas with prominent asteroid bodies. Serum angiotensin-converting enzyme levels were increased in the patient. Conjunctival deposits were the first manifestation of sarcoidosis in the patient and the diagnosis of sarcoidosis was confirmed with a conjunctival biopsy. CONCLUSIONS. To the authors' knowledge, this is the second study that reports a sarcoidosis patient with non-systemic involvement diagnosed after histopathologic analysis of conjunctival deposits.
Açıklama
Anahtar Kelimeler
Conjunctival Deposit, Sarcoidosis, Asteroid Bodies
Kaynak
European Journal of Ophthalmology
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
16
Sayı
1
