The Application of Kidney Injury Molecule-1 to Determine the Duration Between Shockwave Lithotripsy Sessions

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dc.contributor.authorAydin, Hasan R.
dc.contributor.authorIrkilata, Lokman
dc.contributor.authorAydin, Mustafa
dc.contributor.authorDaggulli, Mansur
dc.contributor.authorTaskin, Mehmet H.
dc.contributor.authorDemirel, Huseyin C.
dc.contributor.authorAdanur, Senol
dc.date.accessioned2024-04-24T17:08:01Z
dc.date.available2024-04-24T17:08:01Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: We aimed to evaluate the role of kidney injury molecule-1 (KIM-1) in determining the intervals between shockwave lithotripsy (SWL) sessions. Patients and Methods: This was a prospective, controlled study. It included 40 patients with unilateral kidney stones and 40 healthy persons of a similar age group as controls. The patients' midflow urine samples were collected before SWL and 1 hour, 1 day, 1 week, and 1 month after the procedure. Results: The average age in the SWL and control groups was 4514 and 39 +/- 15 years, respectively (P=0.336). The average KIM-1 value before SWL was 0.74 +/- 0.35ng/mL, which was significantly higher than that of the control group (0.51 +/- 0.14ng/mL) (P<0.001). Similarly, the average values of the urine samples after SWL were higher than those of the control group (P<0.001). When the KIM-1 values of the patients given SWL were compared within the group, the KIM-1 values 1 hour (1.06 +/- 0.51) and 1 day (0.99 +/- 0.67) after the procedure were statistically clearly higher than those before the procedure (P<0.001) and statistically clearly higher than those of the control group (P=0.005). The KIM-1 values 1 week and 1 month after the procedure were not significantly different than the preprocedure values (P=0.652 and P=0.747, respectively). Conclusion: KIM-1 is a noninvasive biomarker that may be used to show renal damage because of stones and early-stage renal damage linked to SWL. In addition, post-SWL KIM-1 values may be used to determine the interval between SWL sessions.en_US
dc.description.sponsorshipSamsun Training and Research Hospitals' Training and Research Foundationen_US
dc.description.sponsorshipWe accepted financial support from Samsun Training and Research Hospitals' Training and Research Foundation for analysis of the KIM-1 levels in this study.en_US
dc.identifier.doi10.1089/end.2015.0379
dc.identifier.endpage113en_US
dc.identifier.issn0892-7790
dc.identifier.issn1557-900X
dc.identifier.issue1en_US
dc.identifier.pmid26407192
dc.identifier.scopus2-s2.0-84954315851
dc.identifier.scopusqualityQ1
dc.identifier.startpage109en_US
dc.identifier.urihttps://doi.org/10.1089/end.2015.0379
dc.identifier.urihttps://hdl.handle.net/11468/17161
dc.identifier.volume30en_US
dc.identifier.wosWOS:000367996100019
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherMary Ann Liebert, Incen_US
dc.relation.ispartofJournal of Endourology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleThe Application of Kidney Injury Molecule-1 to Determine the Duration Between Shockwave Lithotripsy Sessionsen_US
dc.titleThe Application of Kidney Injury Molecule-1 to Determine the Duration Between Shockwave Lithotripsy Sessions
dc.typeArticleen_US

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