Cytokine Responses in Gills of Capoeta umbla as Biomarkers of Environmental Pollution

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dc.contributor.authorDanabas, Durali
dc.contributor.authorYildirim, Nuran Cikcikoglu
dc.contributor.authorYildirim, Numan
dc.contributor.authorOnal, Ayten Oztufekci
dc.contributor.authorUslu, Gulsad
dc.contributor.authorUnlu, Erhan
dc.contributor.authorDanabas, Seval
dc.date.accessioned2024-04-24T17:18:36Z
dc.date.available2024-04-24T17:18:36Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractImmunological biomarkers reflect the effects of exposure to environmental contaminants. In this study, the suitability and sensitivity of cytokine responses, interleukin 1 beta (IL-1 beta), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha) in gill tissues of Capoeta umbla (Heckel, 1843), collected from different regions, as early warning indices of environmental pollution and ecosystem health was evaluated. Fish and water samples were taken from ten stations in March and September 2011 and 2012. Tumor necrosis factor-alpha, IL-1 beta and IL-6 levels were determined in samples of the gill tissues by using an ELISA kit. Significant variations of TNF-alpha, IL-1 beta and IL-6 levels observed between stations and seasons. The results of this study show that seasonal variations of cytokine responses in gills of Capoeta umbla are sensitive to the contaminants present in Uzuncayir Dam Lake (Tunceli, Turkey) water and are valuable biomarkers for environmental pollution and ecosystem health.en_US
dc.description.sponsorshipEnvironment, Atmospheric, Earth and Marine Sciences Research Grant Group (CAYDAG), division of The Scientific and Technological Research Council of Turkey [110Y118]en_US
dc.description.sponsorshipThis study was supported by the Environment, Atmospheric, Earth and Marine Sciences Research Grant Group (CAYDAG), which is a division of The Scientific and Technological Research Council of Turkey (Project no: 110Y118). The authors wish to thank the institution for financial support. This study was carried out under the permission of the Firat University Animal Welfare Committee.en_US
dc.identifier.doi10.2175/106143016X14504669767616
dc.identifier.endpage222en_US
dc.identifier.issn1061-4303
dc.identifier.issn1554-7531
dc.identifier.issue3en_US
dc.identifier.pmid26931532
dc.identifier.scopus2-s2.0-84960389489
dc.identifier.scopusqualityQ1
dc.identifier.startpage217en_US
dc.identifier.urihttps://doi.org/10.2175/106143016X14504669767616
dc.identifier.urihttps://hdl.handle.net/11468/18842
dc.identifier.volume88en_US
dc.identifier.wosWOS:000371530500004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofWater Environment Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUzuncayir Dam Lakeen_US
dc.subjectFishen_US
dc.subjectCytokineen_US
dc.subjectGillsen_US
dc.titleCytokine Responses in Gills of Capoeta umbla as Biomarkers of Environmental Pollutionen_US
dc.titleCytokine Responses in Gills of Capoeta umbla as Biomarkers of Environmental Pollution
dc.typeArticleen_US

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