Platelet-to-lymphocyte ratio is a predictor of long-term mortality in patients with acute coronary syndrome

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dc.authorid0000-0003-2434-6690en_US
dc.authorid0000-0002-1992-7848en_US
dc.authorid0000-0001-7317-2979en_US
dc.contributor.authorOylumlu, Mustafa
dc.contributor.authorOylumlu, Muhammed
dc.contributor.authorArslan, Bayram
dc.contributor.authorPolat, Nihat
dc.contributor.authorÖzbek, Mehmet Nuri
dc.contributor.authorDemir, Muhammed
dc.contributor.authorYıldız, Abdulkadir
dc.contributor.authorToprak, Nizamettin
dc.date.accessioned2021-08-17T06:19:25Z
dc.date.available2021-08-17T06:19:25Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractIntroduction: Atherosclerosis is a chronic inflammatory process and inflammation is an important component of acute coronary syndrome (ACS). Platelet-to-lymphocyte ratio (PLR) is a useful parameter showing the degree of the inflammatory response. Aim: To explore the association between PLR and long-term mortality in patients with ACS. Material and methods: A total of 538 patients who had a diagnosis of ACS between January 2012 and August 2013 were followed up to 60 months. On admission, blood sampling to calculate PLR and detailed clinical data were obtained. Results: In total, 538 patients with a mean age of 61.5 ±13.1 years (69% male) were enrolled in the study. Median follow-up was 79 months (IQR: 74–83 months). Patients were divided into 3 tertiles based on PLR levels. Five-year mortality of the patients was significantly higher among patients in the upper PLR tertile when compared with the lower and middle PLR tertile groups (55 (30.7%) vs. 27 (15.0%) and 34 (19.0%); p < 0.001, p = 0.010 respectively). In the Cox regression analysis, a high level of PLR was an independent predictor of 5-year mortality (OR = 1.005, 95% CI: 1.001–1.008, p = 0.004). Kaplan-Meier analysis according to the long-term mortality-free survival revealed the higher occurrence of mortality in the third PLR tertile group compared to the first (p < 0.001) and second tertiles (p = 0.009). Conclusions: PLR, which is an easily calculated and universally available marker, may be useful in long-term risk classification of patients presenting with ACS.en_US
dc.identifier.citationOylumlu, M., Oylumlu, M., Arslan, B., Polat, N., Özbek, M. N., Demir, M. ve diğerleri. (2020). Platelet-to-lymphocyte ratio is a predictor of long-term mortality in patients with acute coronary syndrome. Postepy w Kardiologii Interwencyjnej, 116(2), 170-176.en_US
dc.identifier.doi10.5114/aic.2020.95859
dc.identifier.endpage176en_US
dc.identifier.issn1734-9338
dc.identifier.issue2en_US
dc.identifier.pmid32636901
dc.identifier.scopus2-s2.0-85088968192
dc.identifier.scopusqualityQ3
dc.identifier.startpage170en_US
dc.identifier.urihttps://www.termedia.pl/Platelet-to-lymphocyte-ratio-is-a-predictor-of-long-term-mortality-in-patients-with-acute-coronary-syndrome,35,40799,0,1.html
dc.identifier.urihttps://hdl.handle.net/11468/7339
dc.identifier.volume116en_US
dc.identifier.wosWOS:000543377400008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorOylumlu, Mustafa
dc.institutionauthorOylumlu, Muhammed
dc.institutionauthorArslan, Bayram
dc.institutionauthorPolat, Nihat
dc.institutionauthorÖzbek, Mehmet Nuri
dc.institutionauthorDemir, Muhammed
dc.institutionauthorToprak, Nizamettin
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltd.en_US
dc.relation.ispartofPostepy w Kardiologii Interwencyjnej
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute coronary syndromeen_US
dc.subjectCoronary heart diseaseen_US
dc.subjectLong-term mortalityen_US
dc.subjectPlatelet-to-lymphocyte ratioen_US
dc.titlePlatelet-to-lymphocyte ratio is a predictor of long-term mortality in patients with acute coronary syndromeen_US
dc.titlePlatelet-to-lymphocyte ratio is a predictor of long-term mortality in patients with acute coronary syndrome
dc.typeArticleen_US

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