Phytochemical fingerprints and bioactivities of ripe disseminules (Fruit-Seeds) of seventeen gundelia (Kenger-Kereng Dikeni) species from Anatolia with chemometric approach

Basit Öğe Kaydı
dc.contributor.authorErtaş, Abdülselam
dc.contributor.authorFırat, Mehmet
dc.contributor.authorYener, İsmail
dc.contributor.authorAkdeniz, Mehmet
dc.contributor.authorYiğitkan, Serkan
dc.contributor.authorBakır, Derya
dc.contributor.authorÇakır, Cansel
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.orcid0000-0002-4090-7227
dc.contributor.orcid0000-0002-0988-9462
dc.contributor.orcid0000-0002-2193-8386
dc.contributor.orcid0000-0002-6202-1515
dc.contributor.orcid0000-0002-0339-635X
dc.date.accessioned2024-04-24T15:59:21Z
dc.date.available2024-04-24T15:59:21Z
dc.date.issued2021
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri, Analitik Kimya Ana Bilim Dalıen_US
dc.description.abstractGundelia species are known as Kenger-kereng dikeni in Anatolia, and their aerial parts are consumed as food. Also, roots and seeds (disseminules) of the Gundelia species are used to prepare gum and coffee. The chemical contents of ethanol and hexane extracts of disseminules of 17 Gundelia species, 13 of them are endemic, were studied using LC/MS/MS and GC/MS. Additionally, their antioxidant potential and enzyme inhibitory capacity against acetyl- and butyryl-cholinesterase, urease, and tyrosinase were determined. The unsaturated fatty acid ratios of Gundelia species were higher than their saturated fatty acid ratio. The highest sum of oleic and linoleic acid was detected in G. tournefortii var. tenuisecta (70.42 %). beta-Sitosterol, alpha-amyrin, 3-acetyllupeol were identified in 17 Gundelia species by GC/MS, while chlorogenic acid and luteolin by LC/MS/MS as major compounds. The ethanol and hexane extracts of G. siirtica, G. rosea, and G. mesopotamica indicated good cholinesterase inhibitory activity. Among all species, ethanol extract of G. colemerikensis exhibited the best activity in ABTS (IC50: 32.30 +/- 0.98 mu g/mL), DPPH (IC50: 59.91 +/- 0.89 mu g/mL), and CUPRAC (A(0.5): 57.41 +/- 1.03 mu g/mL) assays. Ethanol extract of G. colemerikensis also displayed the highest inhibitory activity against butyrylcholinesterase (51.14 +/- 0.25% at 200 mu g/mL), urease (51.71 +/- 1.75% at 200 mu g/mL), and tyrosinase (39.50 +/- 0.85% at 200 mu g/mL) enzymes. According to the chemometric analysis of fatty acids, four groups were observed. Therefore, it is suggested that G. colemerikensis can be used in the pharmaceutical, food, and cosmetic industries due to its antioxidant and enzyme inhibition properties.en_US
dc.description.sponsorshipScientific Research Projects Coordination Unit of Dicle University [Eczaclk.18.004]; Mugla Sitki Kocman University's research fund [17/216]en_US
dc.description.sponsorshipThis study was funded by the Scientific Research Projects Coordination Unit of Dicle University with the Project number: Eczaclk.18.004. Mugla Sitki Kocman University's research fund was also acknowledged with Project number 17/216.en_US
dc.identifier.citationErtaş, A., Fırat, M., Yener, İ., Akdeniz, M., Yiğitkan, S., Bakır, D. ve diğerleri. (2021). Phytochemical fingerprints and bioactivities of ripe disseminules (Fruit-Seeds) of seventeen gundelia (Kenger-Kereng Dikeni) species from Anatolia with chemometric approach. Chemistry and Biodiversity, 18(8), 1-16.
dc.identifier.doi10.1002/cbdv.202100207
dc.identifier.endpage16
dc.identifier.issn1612-1872
dc.identifier.issn1612-1880
dc.identifier.issue8en_US
dc.identifier.pmid34096170
dc.identifier.scopus2-s2.0-85108367968
dc.identifier.scopusqualityQ3
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.1002/cbdv.202100207
dc.identifier.urihttps://hdl.handle.net/11468/14002
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/cbdv.202100207
dc.identifier.volume18en_US
dc.identifier.wosWOS:000664197900001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorErtaş, Abdülselam
dc.institutionauthorYener, İsmail
dc.institutionauthorYiğitkan, Serkan
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofChemistry & Biodiversity
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGundeliaen_US
dc.subjectPhenolic compoundsen_US
dc.subjectFatty acidsen_US
dc.subjectBiological activitiesen_US
dc.subjectGc/Msen_US
dc.subjectLc/Ms/Msen_US
dc.titlePhytochemical fingerprints and bioactivities of ripe disseminules (Fruit-Seeds) of seventeen gundelia (Kenger-Kereng Dikeni) species from Anatolia with chemometric approachen_US
dc.titlePhytochemical fingerprints and bioactivities of ripe disseminules (Fruit-Seeds) of seventeen gundelia (Kenger-Kereng Dikeni) species from Anatolia with chemometric approach
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Phytochemical Fingerprints and Bioactivities of Ripe Disseminules (Fruit-Seeds) of Seventeen Gundelia (Kenger-Kereng Dikeni) Species from Anatolia with Chemometric Approach.pdf
Boyut:
1.2 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu