Protective Ability of Ethanol Extracts of Hypericum scabroides Robson & Poulter and Hypericum triquetrifolium Turra against Protein Oxidation and DNA Damage

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dc.contributor.authorKizil, Goeksel
dc.contributor.authorKizil, Murat
dc.contributor.authorCeken, Bircan
dc.date.accessioned2024-04-24T17:37:51Z
dc.date.available2024-04-24T17:37:51Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe present study was conducted to determine the protective ability of the ethanol extracts of Hypericum scabroides Robson & Poulter (HS) and Hypericum triquetrifolium Turra (HT) against the protein oxidation and DNA damage induced by Fenton system. The ability of HS and HT to prevent oxidative damage to bovine serum albumin (BSA) induced by Fe3+/H2O2 and ascorbic acid was investigated. The ethanol extracts of HS and HT at different concentrations (50-1,000 mu g/mL) efficiently prevented protein oxidation induced by hydroxy radical as assayed by protein oxidation markers including protein carbonyl fort-nation (PCO) and polyacrylamide gel electrophoresis. The effect of ethanol extracts of HS and HT on DNA cleavage induced by UV-photholysis of H2O2 using pBluescript M13+ plasmid DNA were investigated. These extracts significantly inhibited DNA damage induced by reactive oxygen species (ROS). Therefore, HS and HT extracts may be useful in the food industry as effective synthetic antioxidants.en_US
dc.description.sponsorshipDicle University Research Foundation [04-FF-55, 03-FF-63]en_US
dc.description.sponsorshipThis study was supported by Dicle University Research Foundation (Project no: 04-FF-55 and 03-FF-63), Turkey.en_US
dc.identifier.endpage136en_US
dc.identifier.issn1226-7708
dc.identifier.issn2092-6456
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-78650090529
dc.identifier.scopusqualityQ2
dc.identifier.startpage130en_US
dc.identifier.urihttps://hdl.handle.net/11468/21214
dc.identifier.volume18en_US
dc.identifier.wosWOS:000263843200022
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherKorean Society Food Science & Technology-Kosfosten_US
dc.relation.ispartofFood Science and Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectProtein Oxidationen_US
dc.subjectDna Damageen_US
dc.subjectFenton Chemistryen_US
dc.subjectHypericum Scabroidesen_US
dc.subjectHypericum Triquetrifoliumen_US
dc.titleProtective Ability of Ethanol Extracts of Hypericum scabroides Robson & Poulter and Hypericum triquetrifolium Turra against Protein Oxidation and DNA Damageen_US
dc.titleProtective Ability of Ethanol Extracts of Hypericum scabroides Robson & Poulter and Hypericum triquetrifolium Turra against Protein Oxidation and DNA Damage
dc.typeArticleen_US

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