The relationship between complete blood count parameters and Fontaine's Stages in patients with peripheral arterial disease

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dc.contributor.authorDemirtas, Sinan
dc.contributor.authorKarahan, Oguz
dc.contributor.authorYazici, Suleyman
dc.contributor.authorGuclu, Orkut
dc.contributor.authorCaliskan, Ahmet
dc.contributor.authorYavuz, Celal
dc.contributor.authorKucuker, Aslihan
dc.date.accessioned2024-04-24T17:14:44Z
dc.date.available2024-04-24T17:14:44Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: The aim of the present study is to evaluate whether blood count parameters differ according to the stages of Fontaine's classification and to investigate the relationship between hemogram parameters and the severity of the disease. Method: Eighty-two peripheral arterial disease patients were examined prospectively. Patients were classified according to the Fontaine classification system. Fifty newly diagnosed patients were included in the study. The neutrophil-to-lymphocyte ratio, mean platelet volume, and red blood cell distribution width values were recorded. Results: Mean neutrophil-to-lymphocyte ratio values were found to be 3.31 +/- 1.1% in Stage I, 3.11 +/- 1.3% in Stage II, and 3.48 +/- 1.1% in Stage III (p > 0.05). Mean platelet volume values were found to be 7.8 +/- 0.6 fl (Stage I), 8.2 +/- 1.0 fl (Stage II), and 9.0 +/- 0.9 fl (Stage III) (p < 0.05). Red blood cell distribution width values were found to be 13.6 +/- 1.0% in Stage I, 14.8 +/- 1.7% in Stage II, and 15.4 +/- 2.3% in Stage III, being significantly different among all three stages (p < 0.05). Conclusion: Both red blood cell distribution width and mean platelet volume are found to be associated with the severity of atherosclerotic disease in patients with peripheral arterial disease. This finding hypothesizes that complete blood counting parameters may serve as a beneficial and cost-effective method for monitoring atherosclerotic peripheral disease.en_US
dc.identifier.doi10.1177/1708538114522227
dc.identifier.endpage431en_US
dc.identifier.issn1708-5381
dc.identifier.issn1708-539X
dc.identifier.issue6en_US
dc.identifier.pmid24522438
dc.identifier.scopus2-s2.0-84910601082
dc.identifier.scopusqualityQ2
dc.identifier.startpage427en_US
dc.identifier.urihttps://doi.org/10.1177/1708538114522227
dc.identifier.urihttps://hdl.handle.net/11468/18169
dc.identifier.volume22en_US
dc.identifier.wosWOS:000345104400005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofVascular
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectComplete Blood Counting Parametersen_US
dc.subjectNeutrophil-To-Lymphocyte Ratioen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectRed Blood Cell Distribution Widthen_US
dc.subjectPeripheral Arterial Diseaseen_US
dc.titleThe relationship between complete blood count parameters and Fontaine's Stages in patients with peripheral arterial diseaseen_US
dc.titleThe relationship between complete blood count parameters and Fontaine's Stages in patients with peripheral arterial disease
dc.typeArticleen_US

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