Comparison of the effect of periodontal therapy and diode decontamination and periodontal therapy alone on the amount of TNF-alpha in systemically healthy chronic periodontitis patients a non-randomized clinical trial

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dc.authorid0000-0001-6976-2589en_US
dc.authorid0000-0003-2813-1064en_US
dc.authorid0000-0002-3876-5346en_US
dc.authorid0000-0002-7486-232Xen_US
dc.contributor.authorDoğru, Arzum Güler
dc.contributor.authorToprak, Ömer
dc.contributor.authorÜner, Devrim Deniz
dc.contributor.authorİzol, Bozan Serhat
dc.contributor.authorKaplan, İbrahim
dc.contributor.authorDoğru, Mehmet
dc.contributor.authorİpek, Fikret
dc.date.accessioned2022-05-27T08:35:51Z
dc.date.available2022-05-27T08:35:51Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Bölümüen_US
dc.descriptionWOS:000619650600002
dc.description.abstractAbstract OBJECTIVE: To evaluate the outcome of initial periodontal therapy and additional diode laser decontamination therapy on clinical parameters and the amount of tumor necrosis factor alpha (TNF-alpha) in gingival crevicular fluid (GCF) in patients with chronic periodontitis. STUDY DESIGN: The study included 22 patients who were diagnosed with chronic periodontitis and who had at least 1 (>= 5 mm) periodontal pocket in the posterior region of each upper left hemi-arcade. The study was designed as a split-mouth study involving mechanical therapy on the right side and nonsurgical periodontal therapy plus diode laser decontamination therapy on the left side. RESULTS: A statistically significant decrease was observed in clinical parameters at 3 months when compared to the values at baseline in both treatment areas. The change in clinical parameters at 3 months after therapy was not significantly different between the groups (p>0.05). The comparison of GCF TNF-alpha levels at baseline and at 3 months in the 2 treatment areas identified significant changes in the TNF-alpha levels in the hemi-arcade treated with laser diode contamination therapy, whereas the changes in the hemi-arcade treated with nonsurgical periodontal therapy were not significant (p>0.05). A between-group comparison revealed no statistically significant difference at 3 months post-therapy, while the difference at 1 month was found to be statistically significant. CONCLUSION: The study found that laser therapy in addition to nonsurgical periodontal therapy has a positive effect on the clinical parameters and proinflammatory TNF-alpha levels in the early period but makes no contribution in the long term.en_US
dc.identifier.citationDoğru, A.G., Toprak, Ö., Üner, D.D., İzol, B.S., Kaplan, İ., Doğru, M. ve diğerleri. (2020). Comparison of the effect of periodontal therapy and diode decontamination and periodontal therapy alone on the amount of TNF-alpha in systemically healthy chronic periodontitis patients a non-randomized clinical trial. Analytical and Quantitave Cytopathology and Histopathology, 42(6), 180-188.en_US
dc.identifier.endpage188en_US
dc.identifier.issn0884-6812
dc.identifier.issue6en_US
dc.identifier.startpage180en_US
dc.identifier.urihttps://hdl.handle.net/11468/9912
dc.identifier.volume42en_US
dc.identifier.wosWoSIDEksik
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorDoğru, Arzum Güler
dc.institutionauthorToprak, Ömer
dc.institutionauthorKaplan, İbrahim
dc.institutionauthorDoğru, Mehmet
dc.institutionauthorİpek, Fikret
dc.language.isoenen_US
dc.publisherSCI Printers & Publication INCen_US
dc.relation.ispartofAnalytical and Quantitave Cytopathology and Histopathology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic periodontitisen_US
dc.subjectDental plaqueen_US
dc.subjectDental scalingen_US
dc.subjectDental surgeryen_US
dc.subjectDiode laseren_US
dc.subjectGingival crevicular fluiden_US
dc.subjectLasersen_US
dc.subjectNonsurgical periodontal therapyen_US
dc.subjectPeriodontal attachment lossen_US
dc.subjectPeriodontal diseasesen_US
dc.subjectPeriodontal pocketen_US
dc.subjectPeriodontitisen_US
dc.subjectTNF-alphaen_US
dc.subjectTumor necrosis factor alphaen_US
dc.titleComparison of the effect of periodontal therapy and diode decontamination and periodontal therapy alone on the amount of TNF-alpha in systemically healthy chronic periodontitis patients a non-randomized clinical trialen_US
dc.titleComparison of the effect of periodontal therapy and diode decontamination and periodontal therapy alone on the amount of TNF-alpha in systemically healthy chronic periodontitis patients a non-randomized clinical trial
dc.typeArticleen_US

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