Comparison of the effect of periodontal therapy and diode decontamination and periodontal therapy alone on the amount of TNF-alpha in systemically healthy chronic periodontitis patients a non-randomized clinical trial
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Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SCI Printers & Publication INC
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Abstract
OBJECTIVE: To evaluate the outcome of initial periodontal therapy and additional diode laser decontamination therapy on clinical parameters and the amount of tumor necrosis factor alpha (TNF-alpha) in gingival crevicular fluid (GCF) in patients with chronic periodontitis.
STUDY DESIGN: The study included 22 patients who were diagnosed with chronic periodontitis and who had at least 1 (>= 5 mm) periodontal pocket in the posterior region of each upper left hemi-arcade. The study was designed as a split-mouth study involving mechanical therapy on the right side and nonsurgical periodontal therapy plus diode laser decontamination therapy on the left side.
RESULTS: A statistically significant decrease was observed in clinical parameters at 3 months when compared to the values at baseline in both treatment areas. The change in clinical parameters at 3 months after therapy was not significantly different between the groups (p>0.05). The comparison of GCF TNF-alpha levels at baseline and at 3 months in the 2 treatment areas identified significant changes in the TNF-alpha levels in the hemi-arcade treated with laser diode contamination therapy, whereas the changes in the hemi-arcade treated with nonsurgical periodontal therapy were not significant (p>0.05). A between-group comparison revealed no statistically significant difference at 3 months post-therapy, while the difference at 1 month was found to be statistically significant.
CONCLUSION: The study found that laser therapy in addition to nonsurgical periodontal therapy has a positive effect on the clinical parameters and proinflammatory TNF-alpha levels in the early period but makes no contribution in the long term.
Açıklama
WOS:000619650600002
Anahtar Kelimeler
Chronic periodontitis, Dental plaque, Dental scaling, Dental surgery, Diode laser, Gingival crevicular fluid, Lasers, Nonsurgical periodontal therapy, Periodontal attachment loss, Periodontal diseases, Periodontal pocket, Periodontitis, TNF-alpha, Tumor necrosis factor alpha
Kaynak
Analytical and Quantitave Cytopathology and Histopathology
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
42
Sayı
6
Künye
Doğru, A.G., Toprak, Ö., Üner, D.D., İzol, B.S., Kaplan, İ., Doğru, M. ve diğerleri. (2020). Comparison of the effect of periodontal therapy and diode decontamination and periodontal therapy alone on the amount of TNF-alpha in systemically healthy chronic periodontitis patients a non-randomized clinical trial. Analytical and Quantitave Cytopathology and Histopathology, 42(6), 180-188.
