Assessment of Effect of Submucosal Injection of Dexmedetomidine on Postoperative Symptoms

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dc.contributor.authorGursoytrak, Burcu
dc.contributor.authorKocaturk, Ozlem
dc.contributor.authorKoparal, Mahmut
dc.contributor.authorGulsun, Belgin
dc.date.accessioned2024-04-24T16:15:13Z
dc.date.available2024-04-24T16:15:13Z
dc.date.issued2020
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: Embedded third molar surgery is the most frequent oral-maxillofacial surgical procedure performed. The purpose of this study was to assess the clinical effect of submucosal dexmedetomidine (dex) on decreasing postoperative edema, trismus, and pain after surgical molar extraction. Materials and Methods: We carried out a double-blind, randomized, prospective study including patients undergoing surgical bilateral embedded mandibular molar extraction. Patients were divided into 2 groups: those receiving saline solution and those receiving dex. The main outcome measures of pain, facial swelling, and trismus were assessed on days 2 and 7 after surgery In addition, patients were requested to record the time rescue analgesics were taken, as well as the total number taken. The variables were analyzed using the Student t test and a repeated-measures general linear model. P < .05 was considered statistically significant. Results: The study included 40 patients (9 women and 11 men per group; mean age, 23.40 years) undergoing surgical bilateral embedded mandibular molar extraction. On day 2, a statistically significant difference in edema was found between the groups (P = .004). On days 2 and 7, statistically significant differences in the severity of trismus were found between the groups (P = .001 and P < .001, respectively). In addition, statistically significant differences were found between the groups in visual analog scale pain scores at 1, 6, 12, 24, and 48 hours (P = .161, P = .038, P = .110, P = .136, and P = .007, respectively) and in the number of analgesic tablets taken (P < .001). Conclusions: Preoperative submucosal dex is an efficient, safe, and beneficial therapeutic strategy to decrease edema, trismus, and pain after surgical molar extraction. (C) 2019 American Association of Oral and Maxillofacial Surgeonsen_US
dc.identifier.doi10.1016/j.joms.2019.09.024
dc.identifier.endpage371en_US
dc.identifier.issn0278-2391
dc.identifier.issn1531-5053
dc.identifier.issue3en_US
dc.identifier.pmid31689378
dc.identifier.scopus2-s2.0-85075540830
dc.identifier.scopusqualityQ1
dc.identifier.startpage366en_US
dc.identifier.urihttps://doi.org/10.1016/j.joms.2019.09.024
dc.identifier.urihttps://hdl.handle.net/11468/15709
dc.identifier.volume78en_US
dc.identifier.wosWOS:000518367700013
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofJournal of Oral and Maxillofacial Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleAssessment of Effect of Submucosal Injection of Dexmedetomidine on Postoperative Symptomsen_US
dc.titleAssessment of Effect of Submucosal Injection of Dexmedetomidine on Postoperative Symptoms
dc.typeArticleen_US

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