Paramagnetic contribution of serum iron to the spin-spin relaxation rate (1/T2) measured by MRI

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dc.contributor.authorYilmaz, A
dc.contributor.authorYurdakoc, M
dc.contributor.authorBernarding, J
dc.contributor.authorVieth, HM
dc.contributor.authorBraun, J
dc.contributor.authorYurt, A
dc.date.accessioned2024-04-24T15:59:40Z
dc.date.available2024-04-24T15:59:40Z
dc.date.issued2002
dc.departmentDicle Üniversitesien_US
dc.description.abstractSpin-spin relaxation time T-2 values of serum with and without iron were measured by magnetic resonance imaging (MRI) to find the proton relaxivity of Fe(III) in serum. T-2 values in serum containing definite amounts of added iron were also measured before and after addition of ascorbic acid. The difference in the 1/T-2 of serum with and without ascorbic acid was used for recalculation of the added iron values, Recalculated iron values confirm that the difference in healthy serum is caused by iron only. In addition, in order to find the paramagnetic contribution of serum iron, T-2 values of iron-deficient, healthy and iron-overloaded serum were measured before and after addition of ascorbic acid. The difference in the 1/T-2 values was then applied to the calculation of the serum iron values. The consistency of iron values determined from the difference to those by autoanalyzer suggests that the differences in diseased serum also represent the paramagnetic contribution of serum iron. The data imply that serum iron content in healthy, iron-deficient and iron-overloaded serum may be assessed by MRI.en_US
dc.identifier.doi10.1007/BF03170519
dc.identifier.endpage22en_US
dc.identifier.issn0937-9347
dc.identifier.issn1613-7507
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-0036014339
dc.identifier.scopusqualityQ3
dc.identifier.startpage11en_US
dc.identifier.urihttps://doi.org/10.1007/BF03170519
dc.identifier.urihttps://hdl.handle.net/11468/14205
dc.identifier.volume22en_US
dc.identifier.wosWOS:000175659900002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSpringer Wienen_US
dc.relation.ispartofApplied Magnetic Resonance
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleParamagnetic contribution of serum iron to the spin-spin relaxation rate (1/T2) measured by MRIen_US
dc.titleParamagnetic contribution of serum iron to the spin-spin relaxation rate (1/T2) measured by MRI
dc.typeArticleen_US

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