The histological study of osseous regeneration following implantation of various bone graft biomaterials

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dc.contributor.authorAlan, H.
dc.contributor.authorFarahani, E. M. Z.
dc.contributor.authorTunik, S.
dc.contributor.authorKavak, G.
dc.date.accessioned2024-04-24T17:24:14Z
dc.date.available2024-04-24T17:24:14Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: While various biomaterials are used for bone regeneration, the relative comparative efficiency of them has not been thoroughly investigated. Purpose: This study evaluated histopathological events during osseous healing after implantation of following bone grafts: Demineralized freeze-dried cortical bone powder (DFDB), natural coral implants, calcium sulfate-based putty containing demineralized bone matrix (CaS-DBM), and pure-phase beta tricalcium phosphate ceramic granules (-TCP). Materials and Methods: Fifty-six Wistar Albino rats were used for this study. The postimplantation osseous healing was evaluated at 3(rd), 6(th) weeks after the operation. Results: DFDB did not induce bone formation in 3 weeks period, but it showed a highly osteoinductive effect at the end of 6(th) week period. The effects of coral implants on bone formation both at 3 and 6 weeks period were much higher than the DFDB. CaS-DBM showed higher bone formation than -TCP at 3(rd), 6(th) weeks. It was found that coral and CaS-DBM had a more beneficial impact on early bone healing compared to -TCP and DFDB. All these graft biomaterials are useable in human bone defects. The main difference in the ossous healing properties of these materials is observed early postimplantation with the delayed healing outcome being similar.en_US
dc.identifier.doi10.4103/1119-3077.183302
dc.identifier.endpage522en_US
dc.identifier.issn1119-3077
dc.identifier.issue4en_US
dc.identifier.pmid27251971
dc.identifier.scopus2-s2.0-84973345071
dc.identifier.scopusqualityQ2
dc.identifier.startpage517en_US
dc.identifier.urihttps://doi.org/10.4103/1119-3077.183302
dc.identifier.urihttps://hdl.handle.net/11468/19540
dc.identifier.volume19en_US
dc.identifier.wosWOS:000378282700017
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofNigerian Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGraft Materialsen_US
dc.subjectHistological Observationen_US
dc.subjectOsseous Healingen_US
dc.titleThe histological study of osseous regeneration following implantation of various bone graft biomaterialsen_US
dc.titleThe histological study of osseous regeneration following implantation of various bone graft biomaterials
dc.typeArticleen_US

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