Prevalence of antineutrophil cytoplasmic antibody positivity in patients with Hodgkin's and non-Hodgkin lymphoma: a single center experience

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dc.contributor.authorCil, Timucin
dc.contributor.authorAltintas, Abdullah
dc.contributor.authorIsikdogan, Abdurrahman
dc.contributor.authorBatun, Sabri
dc.date.accessioned2024-04-24T16:02:44Z
dc.date.available2024-04-24T16:02:44Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractHematological malignancies are associated with the release of different autoantibodies and rheumatological manifestations. Systemic vasculitides are rare in hematological malignancies, and antineutrophil cytoplasmic antibodies (ANCA) have not been described sufficiently in hematological malignancies. In this present prospective study, we examined the prevalence of ANCA and related disease in Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) patients in the southeast region of Turkey. We examined 119 patients with previously or newly diagnosed NHL and 60 patients with HL for the presence of ANCA and related autoimmune diseases between December 2002 and February 2007. ANCA positivity was detected in only 8 patients (4.4%); and all of these ANCA positivities were detected in patients in the HL group (13.3%); p-ANCA positivity was detected in 6 patients (3.3%); and c-ANCA positivity was detected in 2 patients (1.1%). There was statistically significant difference between patients with HL and NHL in terms of p-ANCA (p = 0.001) but none in c-ANCA (p = 0.111) positivity. None of the ANCA positive patients had vasculitides or rheumatic manifestations. In addition, we did not detect any ANCA positivity in the NHL group. In conclusion, ANCA positivities were detected only in HL patients; but we did not detect the association between ANCA positivities and rheumatic manifestations or vasculitis and also the different treatment responses in HL patients.en_US
dc.identifier.doi10.1007/s12185-009-0341-2
dc.identifier.endpage57en_US
dc.identifier.issn0925-5710
dc.identifier.issn1865-3774
dc.identifier.issue1en_US
dc.identifier.pmid19472034
dc.identifier.scopus2-s2.0-70350571264
dc.identifier.scopusqualityQ3
dc.identifier.startpage52en_US
dc.identifier.urihttps://doi.org/10.1007/s12185-009-0341-2
dc.identifier.urihttps://hdl.handle.net/11468/14896
dc.identifier.volume90en_US
dc.identifier.wosWOS:000267662100011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Japan Kken_US
dc.relation.ispartofInternational Journal of Hematology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntineutrophil Cytoplasmic Antibodiesen_US
dc.subjectHodgkin's Lymphomaen_US
dc.subjectNon-Hodgkin Lymphomaen_US
dc.subjectVasculitisen_US
dc.titlePrevalence of antineutrophil cytoplasmic antibody positivity in patients with Hodgkin's and non-Hodgkin lymphoma: a single center experienceen_US
dc.titlePrevalence of antineutrophil cytoplasmic antibody positivity in patients with Hodgkin's and non-Hodgkin lymphoma: a single center experience
dc.typeArticleen_US

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