Impact of Collagen Cross-linking on Psychological Distress and Vision and Health-Related Quality of Life in Patients With Keratoconus

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dc.contributor.authorCingu, Abdullah Kursat
dc.contributor.authorBez, Yasin
dc.contributor.authorCinar, Yasin
dc.contributor.authorTurkcu, Fatih Mehmet
dc.contributor.authorYildirim, Adnan
dc.contributor.authorSahin, Alparslan
dc.contributor.authorTas, Cuma
dc.date.accessioned2024-04-24T17:08:17Z
dc.date.available2024-04-24T17:08:17Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: To evaluate the changes in psychological distress level and quality of life (QoL) scores of keratoconus (KC) patients 1 year after corneal collagen cross-linking (CXL). Methods: Observational cross-sectional study. Thirty-three, consecutive progressive KC patients who received CXL treatment were enrolled in the study. All patients were evaluated before and 1 year after CXL ophthalmologically and psychologically. Main outcome measures were the visual, refractive, and topographic changes and the Beck Depression Inventory, State-Trait Anxiety Inventory (STAI), Short Form-36 (SF-36), and The National Eye Institute Visual Function Questionnaire (NEI-VFQ-25). Results: There were significant improvements in the keratometric readings at flat axis, steep axis, the mean keratometric reading, the corneal astigmatism (K-ast), and the maximum keratometric reading. State-Trait Anxiety Inventory-II scores, QoL dimensions, such as physical role difficulty, general health, mental health, ocular pain, near activities, distance activities, peripheral vision, and mental health scores, and the composite score of NEI-VFQ-25, were higher after surgery. There was a positive correlation between the changes observed in K-ast and mental health; a negative correlation between the changes in K-ast and STAI-II, and a negative correlation between the changes in mental health and STAI-II. Change in STAI-II has significantly predicted the improvement observed in general health. Conclusions: Our results suggested lower trait anxiety and better vision-related and health-related QoL in KC patients 1 year after successful CXL treatment. Better QoL in these patients seems to be related not only with the visual and refractive results but also improvement observed in trait anxiety.en_US
dc.identifier.doi10.1097/ICL.0000000000000129
dc.identifier.endpage353en_US
dc.identifier.issn1542-2321
dc.identifier.issn1542-233X
dc.identifier.issue6en_US
dc.identifier.pmid25794329
dc.identifier.scopus2-s2.0-84946733517
dc.identifier.scopusqualityQ1
dc.identifier.startpage349en_US
dc.identifier.urihttps://doi.org/10.1097/ICL.0000000000000129
dc.identifier.urihttps://hdl.handle.net/11468/17281
dc.identifier.volume41en_US
dc.identifier.wosWOS:000364381000005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofEye & Contact Lens-Science and Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnxietyen_US
dc.subjectCollagen Cross-Linkingen_US
dc.subjectDepressionen_US
dc.subjectKeratoconusen_US
dc.subjectQuality Of Lifeen_US
dc.titleImpact of Collagen Cross-linking on Psychological Distress and Vision and Health-Related Quality of Life in Patients With Keratoconusen_US
dc.titleImpact of Collagen Cross-linking on Psychological Distress and Vision and Health-Related Quality of Life in Patients With Keratoconus
dc.typeArticleen_US

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