Relationship between psychological status and disease activity and quality of life in ankylosing spondylitis

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dc.contributor.authorBaysal, Ozlem
dc.contributor.authorDurmus, Bekir
dc.contributor.authorErsoy, Yuksel
dc.contributor.authorAltay, Zuhal
dc.contributor.authorSenel, Kazim
dc.contributor.authorNas, Kemal
dc.contributor.authorUgur, Mahir
dc.date.accessioned2024-04-24T16:00:04Z
dc.date.available2024-04-24T16:00:04Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractOur aim in this study was to compare the depression and anxiety risk in patients with AS and healthy controls and also to determine the relationship between disease activity, quality of life and psychological well-being. Two hundred and forty-three patients with ankylosing spondylitis (AS) and 118 age-, sex- and education-matched healthy controls were enroled into the study. Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), and Functional Index, and Metrology Index, Health Assessment Questionnaire for Spondyloarthropathies (HAQ-S), Hospital Anxiety and Depression Scale (HADS) including depression subscale (HADS-D) and anxiety subscale (HADS-A), Ankylosing Spondylitis Quality of Life (ASQoL) Scale, duration of morning stiffness, pain-visual analogue scale (VAS), patient and physician's global assessment of disease activity (100 mm VAS) were used to assess clinical and psychological status. Patients had similar HADS-D but higher HADS-A than healthy controls. Patients with high risk for depression and anxiety had higher scores in BASDAI, BASFI and also poorer scores in VAS pain, patient global assessment, physician global assessment, HAQ-S and ASQoL. There was a negative correlation of HADS-D and HADS-A scores with educational level of the patients. Higher scores in HADS-D and HADS-A indicated poorer functional outcome and quality of life. Multivariate logistic regression analysis revealed that the HADS-D (OR = 6.84), HAQ-S (OR = 1.76), VAS pain score (OR = 1.03) and ESR (OR = 1.02) were independent risk factors for higher anxiety scores whereas HADS-A (OR = 1.36) and ASQoL (OR = 1.24) were independent risk factors for higher depression scores. The psychological status had close interaction with disease activity and quality of life in patients with AS.en_US
dc.identifier.doi10.1007/s00296-010-1381-x
dc.identifier.endpage800en_US
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.issue6en_US
dc.identifier.pmid20221605
dc.identifier.scopus2-s2.0-79959989505
dc.identifier.scopusqualityQ1
dc.identifier.startpage795en_US
dc.identifier.urihttps://doi.org/10.1007/s00296-010-1381-x
dc.identifier.urihttps://hdl.handle.net/11468/14360
dc.identifier.volume31en_US
dc.identifier.wosWOS:000290989300015
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofRheumatology International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDepressionen_US
dc.subjectAnxietyen_US
dc.subjectDisease Activityen_US
dc.subjectQuality Of Lifeen_US
dc.subjectAnkylosing Spondylitisen_US
dc.titleRelationship between psychological status and disease activity and quality of life in ankylosing spondylitisen_US
dc.titleRelationship between psychological status and disease activity and quality of life in ankylosing spondylitis
dc.typeArticleen_US

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