Identification of interleukin 2, 6, and 8 levels around miniscrews during orthodontic tooth movement

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dc.contributor.authorHamamci, Nihal
dc.contributor.authorKaya, Filiz Acun
dc.contributor.authorUysal, Ersin
dc.contributor.authorYokus, Beran
dc.date.accessioned2024-04-24T17:08:05Z
dc.date.available2024-04-24T17:08:05Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of this study was to identify the levels of interleukin (IL)-2, IL-6, and IL-8 around miniscrews used for anchorage during canine distalization. Sixteen patients (eight males and eight females; mean age, 16.6 +/- 2.4 years) who were treated with bilateral upper first premolar extractions were included in the study. Thirty-two maxillary miniscrew implants were placed bilaterally in the alveolar bone between the maxillary second premolars and first molars as anchorage units for maxillary canine distalization. Three groups were constructed. The treatment, miniscrew, and control groups consisted of upper canines, miniscrew implants, and upper second premolars, respectively. Peri-miniscrew implant crevicular fluid and gingival crevicular fluid (GCF) were obtained at baseline (T1) and at 1 (T2), 24 (T3), and 48 (T4) hours, 7 (T5) and 21 (T6) days, and 3 months (T7) after force application. Paired sample t-tests were used to determine within-group changes and Dunnett's t and Tukey's honestly significant difference tests for between-group multiple comparisons. During the 3 month period, IL-2 levels significantly increased (P < 0.01) but only in the treatment group after 24 hours. IL-6 levels were unchanged at all times points in the three groups. IL-8 levels increased significantly at 1 (P < 0.05), 24 (P < 0.01), and 48 (P < 0.01) hours in the treatment group and at 24 (P < 0.05) and 48 (P < 0.01) hours in the miniscrew group. It appears that miniscrews can be used for anchorage in orthodontics when correct physiological forces are applied.en_US
dc.identifier.doi10.1093/ejo/cjr019
dc.identifier.endpage361en_US
dc.identifier.issn0141-5387
dc.identifier.issn1460-2210
dc.identifier.issue3en_US
dc.identifier.pmid21474566
dc.identifier.scopus2-s2.0-84861589889
dc.identifier.scopusqualityQ1
dc.identifier.startpage357en_US
dc.identifier.urihttps://doi.org/10.1093/ejo/cjr019
dc.identifier.urihttps://hdl.handle.net/11468/17194
dc.identifier.volume34en_US
dc.identifier.wosWOS:000304542800016
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofEuropean Journal of Orthodontics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keyword]en_US
dc.titleIdentification of interleukin 2, 6, and 8 levels around miniscrews during orthodontic tooth movementen_US
dc.titleIdentification of interleukin 2, 6, and 8 levels around miniscrews during orthodontic tooth movement
dc.typeArticleen_US

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