Values of troponin T and myoglobin predictive of non-cardiac ischemia in rats

Basit Öğe Kaydı
dc.contributor.authorGuclu, Orkut
dc.contributor.authorCaliskan, Ahmet
dc.contributor.authorKarahan, Oguz
dc.contributor.authorDemirtas, Sinan
dc.contributor.authorYazici, Suleyman
dc.contributor.authorYavuz, Celal
dc.contributor.authorMavitas, Binali
dc.date.accessioned2024-04-24T17:40:01Z
dc.date.available2024-04-24T17:40:01Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective(s): Biochemical markers are important for the timely diagnosis and follow-up of ischemic events. Most of the markers have been previously studied in the context of cardiac ischemia. However, research on markers of non-cardiac events has been insufficient. Therefore, we investigated the relationship between troponin and myoglobin which are commonly used markers of cardiac ischemia, in non-cardiac ischemia. Materials and Methods: Forty-eight rats were equally divided into six groups. Group I was the control group. Group II was the sham group and received a simple laparotomy. The superior mesenteric artery was clamped in groups III and IV in order to create mesenteric ischemia. The left femoral artery was clamped in groups V and VI in order to create peripheral ischemia. Intracardiac blood samples were taken from all groups (during the 3rd hour of ischemia in groups III and V and the 6th hour of ischemia in group IV and VI) and troponin T and myoglobin levels were measured. Results: Troponin and myoglobin levels were statistically similar in groups I and II. Moreover, increments were detected for troponin and myoglobin in ischemia groups according to group I and II. Furthermore, higher troponin Tlevels were detected after three hours of mesenteric ischemia and higher myoglobin values were observed after six hours of mesenteric ischemia (P<0.05). Conclusion: Troponin T and myoglobin are not specific for non-cardiac ischemia, and they may be useful for detecting other ischemic events.en_US
dc.identifier.endpage321en_US
dc.identifier.issn2008-3866
dc.identifier.issn2008-3874
dc.identifier.issue5en_US
dc.identifier.pmid24967059
dc.identifier.scopus2-s2.0-84901190993
dc.identifier.scopusqualityQ2
dc.identifier.startpage318en_US
dc.identifier.urihttps://hdl.handle.net/11468/21526
dc.identifier.volume17en_US
dc.identifier.wosWOS:000345354000002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherMashhad Univ Med Sciencesen_US
dc.relation.ispartofIranian Journal of Basic Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMesenteric Ischemiaen_US
dc.subjectMyoglobinen_US
dc.subjectPeripheral Ischemiaen_US
dc.subjectTroponin Ten_US
dc.titleValues of troponin T and myoglobin predictive of non-cardiac ischemia in ratsen_US
dc.titleValues of troponin T and myoglobin predictive of non-cardiac ischemia in rats
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu