Risk factors for hepatocellular carcinoma in Turkey

Basit Öğe Kaydı
dc.contributor.authorUzunalimoglu, Ö
dc.contributor.authorYurdaydin, C
dc.contributor.authorÇetinkaya, H
dc.contributor.authorBozkaya, H
dc.contributor.authorSahin, T
dc.contributor.authorÇolakoglu, S
dc.contributor.authorTankurt, E
dc.date.accessioned2024-04-24T16:19:09Z
dc.date.available2024-04-24T16:19:09Z
dc.date.issued2001
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe contribution of hepatitis B, hepatitis C, and excess alcohol intake to the development of hepatocellular carcinoma in Turkey was assessed. The study was conducted through a questionnaire sent to seven major medical referral centers in different regions of Turkey and is based on 207 patients seen in the period 1994-1997. Of the seven centers, two were located in West Turkey (54 patients), two were in Central Turkey (85 patients), and two were in south and southeast Turkey (68 patients). In 196 of the 207 patients (94.7%), there was a history of chronic liver disease, and in 180 patients (87%) liver cirrhosis was documented, Of the 207 patients, 116 (56%) had hepatitis B, 48 (23.2%) had hepatitis C and 33 (15.9%) had a history of excess alcohol intake. Anti-delta testing was available in 69 of 116 patients with hepatitis B, and anti-HDV was positive in 13 of these patients (13/69, 18.8%). Of the 33 patients with a history of heavy alcohol intake, 18 had concomitant chronic viral hepatitis infection, and alcohol alone was the etiology of hepatocellular carcinoma in only 15 cases (7.2%). The distribution of etiologic factors was not homogenous in different geographical regions ill Turkey. In central, south, and southeastern Turkey, the predominant etiology of hepatocellular carcinoma was hepatitis B, whereas in western Turkey the impact of hepatitis B, hepatitis C, and alcohol was similar. This study indicates that hepatitis B virus infection is the leading cause of hepatocellular carcinoma in Turkey, followed by hepatitis C infection and alcoholic liver disease.en_US
dc.identifier.doi10.1023/A:1010705910858
dc.identifier.endpage1028en_US
dc.identifier.issn0163-2116
dc.identifier.issn1573-2568
dc.identifier.issue5en_US
dc.identifier.pmid11341644
dc.identifier.scopus2-s2.0-0035034014
dc.identifier.scopusqualityQ1
dc.identifier.startpage1022en_US
dc.identifier.urihttps://doi.org/10.1023/A:1010705910858
dc.identifier.urihttps://hdl.handle.net/11468/16414
dc.identifier.volume46en_US
dc.identifier.wosWOS:000168472700015
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofDigestive Diseases and Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatocellular Carcinomaen_US
dc.subjectHepatitis Ben_US
dc.subjectHepatitis Cen_US
dc.subjectAlcoholen_US
dc.subjectTurkeyen_US
dc.titleRisk factors for hepatocellular carcinoma in Turkeyen_US
dc.titleRisk factors for hepatocellular carcinoma in Turkey
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu