Prognostic significance of pretreatment serum lactate dehydrogenase-to-albumin ratio in gastric cancer
dc.authorid | 0000-0002-3161-0923 | en_US |
dc.authorid | 0000-0002-9178-7843 | en_US |
dc.contributor.author | Aday, Ulaş | |
dc.contributor.author | Tatlı, Faruk | |
dc.contributor.author | Akpulat, Faik V. | |
dc.contributor.author | İnan, Mazlum | |
dc.contributor.author | Kafadar, Mehmet Tolga | |
dc.contributor.author | Bilge, Hüseyin | |
dc.contributor.author | Başol, Ömer | |
dc.contributor.author | Oǧuz, Abdullah | |
dc.date.accessioned | 2021-07-30T05:55:01Z | |
dc.date.available | 2021-07-30T05:55:01Z | |
dc.date.issued | 2020 | en_US |
dc.department | Dicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı | en_US |
dc.description | WOS:000615631000001 | |
dc.description | PMID: 33235539 | |
dc.description.abstract | Aim of the study: To investigate the prognostic role of lactate dehydrogenase-to-albumin ratio (LAR) in gastric cancer patients undergoing curative resection. Material and methods: A retrospective study was conducted including resectable gastric cancer patients. According to the time-dependent receiver operating characteristics (ROC) analysis, the optimal threshold for pretreatment LAR was 5.5. The Kaplan-Meier method, Cox regression univariate and multivariate analyses were used to analyze the prognostic factors for disease-free survival and overall survival (OS). Results: The study cohort consisted of 81 patients, mean age was 60.2 ±13.8 (range, 29-87) years and 55 (67.9%) were male. The median OS time was 34.8 and 45 months in patients with LAR ≥ 5.5 (n = 50) and LAR < 5.5 (n = 31), respectively. Kaplan-Meier curves showed that with the increase in LAR there was reduced survival, but it was not statistically significant (p = 0.278). Multivariate analyses revealed that the positive lymph node ratio above 20% was an independent predictor in resectable gastric cancer patients (OR = 6.281, 95% CI: 1.135-34.767, p = 0.035). Conclusions: With the increase in LAR survival in gastric cancer decreased, but it was not statistically significant. Studies involving a large patient series are needed. | en_US |
dc.identifier.citation | Aday, U., Tatlı, F., Akpulat, F. V., İnan, M., Kafadar, M. T., Bilge, H. ve diğerleri. (2020). Prognostic significance of pretreatment serum lactate dehydrogenase-to-albumin ratio in gastric cancer. Wspolczesna Onkologia, 24(3), 145-149. | en_US |
dc.identifier.doi | 10.5114/wo.2020.100219 | |
dc.identifier.endpage | 149 | en_US |
dc.identifier.issn | 1428-2526 | |
dc.identifier.issue | 3 | en_US |
dc.identifier.pmid | 33235539 | |
dc.identifier.scopus | 2-s2.0-85095875181 | |
dc.identifier.scopusquality | Q2 | |
dc.identifier.startpage | 145 | en_US |
dc.identifier.uri | https://www.termedia.pl/Prognostic-significance-of-pretreatment-serum-lactate-dehydrogenase-to-albumin-ratio-in-gastric-cancer,3,42181,0,1.html | |
dc.identifier.uri | https://hdl.handle.net/11468/7256 | |
dc.identifier.volume | 24 | en_US |
dc.identifier.wos | WOS:000615631000001 | |
dc.identifier.wosquality | N/A | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.indekslendigikaynak | PubMed | |
dc.institutionauthor | Aday, Ulaş | |
dc.institutionauthor | Tatlı, Faruk | |
dc.institutionauthor | Akpulat, Faik V. | |
dc.institutionauthor | İnan, Mazlum | |
dc.institutionauthor | Kafadar, Mehmet Tolga | |
dc.institutionauthor | Bilge, Hüseyin | |
dc.institutionauthor | Başol, Ömer | |
dc.institutionauthor | Oǧuz, Abdullah | |
dc.language.iso | en | en_US |
dc.publisher | Termedia Publishing House Ltd. | en_US |
dc.relation.ispartof | Wspolczesna Onkologia | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Curative surgery | en_US |
dc.subject | Gastric cancer | en_US |
dc.subject | LAR | en_US |
dc.subject | Survival | en_US |
dc.title | Prognostic significance of pretreatment serum lactate dehydrogenase-to-albumin ratio in gastric cancer | en_US |
dc.title | Prognostic significance of pretreatment serum lactate dehydrogenase-to-albumin ratio in gastric cancer | |
dc.type | Article | en_US |
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