Correlation of Tumour Markers in Ascitic Fluid and Serum: Are Measurements of Ascitic Tumour Markers a Futile Attempt?

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dc.contributor.authorTuzun, Y.
dc.contributor.authorCelik, Y.
dc.contributor.authorBayan, K.
dc.contributor.authorYilmaz, S.
dc.contributor.authorDursun, M.
dc.contributor.authorCanoruc, F.
dc.date.accessioned2024-04-24T17:14:43Z
dc.date.available2024-04-24T17:14:43Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractCorrelations between tumour markers in ascitic fluid and serum were investigated to determine whether ascitic fluid analysis had any diagnostic advantage over serum in 91 adults with ascites (55 malign; 36 benign). Serum and ascitic fluid were analysed for carcinoembryonic antigen (CEA), cancer antigen (CA) 125, CA19.9, CA72.4, CA15.3, alpha-fetoprotein (AFP) and cytokeratin-19 fragment (CYFRA). The tumour markers were skewed between the groups so were logarithmically transformed. Correlations between serum and ascitic fluid were tested using Pearson's correlation coefficient. Serum and ascitic fluid levels of CEA, CA125, CYFRA and AFP in the malign group were statistically different and CEA, CA19.9, CA5.3, CYFRA and AFP were statistically different in the benign group. For both groups, all tumour markers were highly correlated in serum and ascitic fluid, with the exception of CYFRA in the malign group. These results indicate that, where malignant ascites is suspected, analysing tumour markers in ascitic fluid does not have any advantage over serum analysis.en_US
dc.identifier.doi10.1177/147323000903700109
dc.identifier.endpage86en_US
dc.identifier.issn0300-0605
dc.identifier.issue1en_US
dc.identifier.pmid19215676
dc.identifier.scopus2-s2.0-64149095861
dc.identifier.scopusqualityQ2
dc.identifier.startpage79en_US
dc.identifier.urihttps://doi.org/10.1177/147323000903700109
dc.identifier.urihttps://hdl.handle.net/11468/18155
dc.identifier.volume37en_US
dc.identifier.wosWOS:000264163500009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherField House Publishing Llpen_US
dc.relation.ispartofJournal of International Medical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAscitesen_US
dc.subjectTumour Markersen_US
dc.subjectCorrelationen_US
dc.titleCorrelation of Tumour Markers in Ascitic Fluid and Serum: Are Measurements of Ascitic Tumour Markers a Futile Attempt?en_US
dc.titleCorrelation of Tumour Markers in Ascitic Fluid and Serum: Are Measurements of Ascitic Tumour Markers a Futile Attempt?
dc.typeArticleen_US

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