Mid-term outcomes of surgical treatment in fractures in patients with osteopetrosis

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dc.contributor.authorYigit, S.
dc.contributor.authorArslan, H.
dc.contributor.authorAkar, M. S.
dc.contributor.authorSahin, M. A.
dc.date.accessioned2024-04-24T17:15:18Z
dc.date.available2024-04-24T17:15:18Z
dc.date.issued2020
dc.departmentDicle Üniversitesien_US
dc.description.abstractAims Osteopetrosis (OP) is a rare hereditary disease that causes reduced bone resorption and increased bone density as a result of osteoclastic function defect. Our aim is to review the difficulties, mid-term follow-up results, and literature encountered during the treatment of OP. Methods This is a retrospective and observational study containing data from nine patients with a mean age of 14.1 years (9 to 25; three female, six male) with OP who were treated in our hospital between April 2008 and October 2018 with 20 surgical procedures due to 17 different fractures. Patient data included age, sex, operating time, length of stay, genetic type of the disease, previous surgery, fractures, complications, and comorbidity. Results The mean follow-up period was 92.5 months (25 to 140). Bony union was observed in all of our patients. Osteomyelitis developed in two patients with femoral shaft fractures, and two patients had peri-implant stress fractures. Conclusion Treatment of fractures in OP patients is difficult, healing is protracted, and the risk of postoperative infection is high. In children and young adults with OP who have open medullary canal and the epiphyses are not closed, fractures can be treated with surgical techniques such as intramedullary titanium elastic nail (TENS) technique or fixation with Kirschner (K)-wire.en_US
dc.identifier.doi10.1302/0301-620X.102B8.BJJ-2020-0431.R1
dc.identifier.endpage1087en_US
dc.identifier.issn2049-4394
dc.identifier.issue8en_US
dc.identifier.pmid32731834en_US
dc.identifier.scopus2-s2.0-85088885400en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1082en_US
dc.identifier.urihttps://doi.org/10.1302/0301-620X.102B8.BJJ-2020-0431.R1
dc.identifier.urihttps://hdl.handle.net/11468/18404
dc.identifier.volume102Ben_US
dc.identifier.wosWOS:000561876000015
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherBritish Editorial Soc Bone & Joint Surgeryen_US
dc.relation.ispartofBone & Joint Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleMid-term outcomes of surgical treatment in fractures in patients with osteopetrosisen_US
dc.typeArticleen_US

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