Relationship between catheter related cerebrospinal fluid infections and systemic immune-inflammation index

dc.authorid0000-0002-0166-9668en_US
dc.contributor.authorNergiz, Şebnem
dc.contributor.authorÖztürk, Pınar Aydın
dc.date.accessioned2023-10-26T08:08:46Z
dc.date.available2023-10-26T08:08:46Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Atatürk Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümüen_US
dc.description.abstractBackground. This study investigated the relationship between the systemic immune inflammation index (SII) and catheter-related infections and their effects on prognosis in pediatric patients. Methods. A total of 56 pediatric patients diagnosed with ventriculoperitoneal (VP) shunt infection between January 2017 and October 2019 were included. V-P shunt infection diagnosis was made based on clinical findings. All cerebrospinal fluid (CSF) samples were subjected to direct microscopic examination and culture. Protein, glucose, and sodium levels in CSF, CSF leukocytes, and hematological and biochemical parameters were measured. Results. Fifty-six patients with growth in CSF culture were included in this study. 55.4% of the cases were female and 44.6% male. V-P shunt was detected in 82.1% of the cases and external ventricular drainage (EVD) catheter-related infection in 17.9%. The CSF/blood glucose ratio was significantly lower (p = 0.046), and SII was significantly increased (p = 0.002) in non-coagulase-negative staphylococci. Conclusions. Early and appropriate antibiotic therapy reduces morbidity and mortality in catheter-related infections. However, it is important to start empirical antibiotherapy until culture results are expected. Therefore, further research on the estimation of possible factors is needed.en_US
dc.identifier.citationNergiz, Ş. ve Öztürk, P. A. (2023). Relationship between catheter related cerebrospinal fluid infections and systemic immune-inflammation index. PeerJ, 9, 1-12.en_US
dc.identifier.doi10.7717/peerj.15905
dc.identifier.endpage12en_US
dc.identifier.issn2167-8359
dc.identifier.pmid37701835
dc.identifier.scopus2-s2.0-85171995301
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urifile:///C:/Users/Rojbin/Downloads/peerj-15905.pdf
dc.identifier.urihttps://hdl.handle.net/11468/12952
dc.identifier.volume9en_US
dc.identifier.wosWOS:001088800300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorNergiz, Şebnem
dc.language.isoenen_US
dc.publisherPeerJ Inc.en_US
dc.relation.ispartofPeerJ
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHydrocephalusen_US
dc.subjectInfectionen_US
dc.subjectSystemic immune inflammation indexen_US
dc.subjectVentriculoperitoneal shunten_US
dc.titleRelationship between catheter related cerebrospinal fluid infections and systemic immune-inflammation indexen_US
dc.titleRelationship between catheter related cerebrospinal fluid infections and systemic immune-inflammation index
dc.typeArticleen_US

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