A novel predictor in endovascular treatment patients for cerebral perfusion and prognosis: CHA2DS2-VASC

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dc.authorid0000-0003-2243-6190en_US
dc.authorid0000-0002-9049-7123en_US
dc.authorid0000-0003-4326-6418en_US
dc.authorid0000-0001-9394-4999en_US
dc.contributor.authorÖzbek, Mehmet
dc.contributor.authorArık, Baran
dc.contributor.authorDemir, Muhammed
dc.contributor.authorBilik, Mehmet Zihni
dc.contributor.authorAkıl, Mehmet Ata
dc.contributor.authorDemir, Fidel
dc.contributor.authorGültekin, Hamza
dc.contributor.authorAkıl, Eşref
dc.date.accessioned2024-01-03T06:11:20Z
dc.date.available2024-01-03T06:11:20Z
dc.date.issued2022en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractObjective: Thrombolysis in Cerebral Infarction(TICI) score is used to objectively evaluate cerebral perfusion after intervention in acute stroke with mechanical thrombectomy. In our study, we aimed to compare the results of patients with successful TICI perfusion score (TICI ≥ 2c) with the results of patients with poor TICI perfusion score (TICI < 2c) and to investigate the relationship of the CHA2DS2-VASc scoring system with the final TICI perfusion score and other endpoints. Methods: For this retrospective, single-center, cross-sectional study, 278 patients who underwent endovascular thrombectomy were screened consecutively by the interventional neurology department of hospital. The primary endpoint of the study was in-hospital and 1-year all-cause death. All patients underwent cranial imaging to evaluate hemorrhagic transformation after the procedure. Results: It was observed that CHA2DS2-VASc score was significantly higher in the poor cerebral perfusion group than in the succesful cerebral perfusion group (3.19 ± 1.8 vs 2.72 ± 1.73, p = 0.046). According to Kaplan Meier's analysis, a significant difference was observed in the group with a CHA2DS2-VASc score > 2.5 in terms of all-cause mortality at follow-up compared to the group with a low CHA2DS2-VASc score (p = 0.002). According to Kaplan Meier's analysis, a significant difference was observed in the group with a poor TICI score compared to the group with a succesful one in terms of all-cause mortality at follow-up (p < 0.001). Cox regression model showed that poor TICI score group, Age ≥ 75 years, lower glomerular filtariton rate (GFR), higher high-sensitive C-reactive protein (Hs-CRP), and higher admission NIHSS score were independent predictors of 1-year all-cause mortality. Conclusion: High CHA2DS2-VASc score has been shown to be a predictor of unsuccessful cerebral perfusion score and 1-year mortality after mechanical thrombectomy in stroke patients. As a result of our research, it has been shown that complete or nearly complete reperfusion has more positive results than partial reperfusion.en_US
dc.identifier.citationÖzbek, M., Arık, B., Demir, M., Bilik, M. Z., Akıl, M. A., Demir, F. ve diğerleri. (2022). A novel predictor in endovascular treatment patients for cerebral perfusion and prognosis: CHA2DS2-VASC. Journal of Clinical Neuroscience, 106, 1-7.en_US
dc.identifier.doi10.1016/j.jocn.2022.10.003
dc.identifier.endpage7en_US
dc.identifier.issn0967-5868
dc.identifier.pmid36228502
dc.identifier.scopus2-s2.0-85139731132
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S096758682200385X?via%3Dihub
dc.identifier.urihttps://hdl.handle.net/11468/13132
dc.identifier.volume106en_US
dc.identifier.wosWOS:000868295200001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzbek, Mehmet
dc.institutionauthorArık, Baran
dc.institutionauthorDemir, Muhammed
dc.institutionauthorBilik, Mehmet Zihni
dc.institutionauthorAkıl, Mehmet Ata
dc.institutionauthorGültekin, Hamza
dc.institutionauthorAkıl, Eşref
dc.language.isoenen_US
dc.publisherChurchill Livingstoneen_US
dc.relation.ispartofJournal of Clinical Neuroscience
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCerebral perfusionen_US
dc.subjectCHA2DS2-VASc scoreen_US
dc.subjectEndovascular treatmenten_US
dc.subjectStrokeen_US
dc.subjectTICI scoreen_US
dc.titleA novel predictor in endovascular treatment patients for cerebral perfusion and prognosis: CHA2DS2-VASCen_US
dc.titleA novel predictor in endovascular treatment patients for cerebral perfusion and prognosis: CHA2DS2-VASC
dc.typeArticleen_US

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