Antimicrobial susceptibility testing of Arcobacter butzleri and Arcobacter cryaerophilus isolated from buffalo milk with subclinical mastitis: A different approach

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dc.authorid0000-0002-9017-763Xen_US
dc.authorid0000-0002-2952-5180en_US
dc.contributor.authorAltan, Feray
dc.contributor.authorAlp, Simten Yeşilmen
dc.date.accessioned2024-03-19T10:43:05Z
dc.date.available2024-03-19T10:43:05Z
dc.date.issued2022en_US
dc.departmentDicle Üniversitesi, Veteriner Fakültesi, Klinik Öncesi Bilimler Bölümü, Farmakoloji ve Toksikoloji Ana Bilim Dalıen_US
dc.description.abstractThe aim of to our study was the minimum inhibitory concentrations (MICs) of nine antimicrobials in current use and three potentially new alternatives against Arcobacter spp. isolated from dairy buffalos with subclinical mastitis, and to evaluate these parameters instead of pharmacokinetic parameters. The Arcobacter spp. isolates were isolated from milk samples collected from dairy buffalos with subclinical mastitis. The susceptibility of Arcobacterspp. strains to antimicrobials were performed according to the guidelines by the NCCLS. The MIC value of vancomycin, erythromycin and tetracycline were not determined, and MIC value of ceftiofur, spiramycin and gentamicin have showed wide variations for isolated strains. However, cefquinome, tylosin, enrofloxacin and florfenicol were determined the best-performing agents against these strains. Antibiotics show concentration and time dependent killing, and studies have demonstrated the AUC/MIC, Cmax/MIC and t MIC ratios to be the best diviner of antibacterial effect. In the present study, based on the MIC values determined for selected antimicrobial agents, and pharmacokinetic parameters, amoxicillin, ceftiofur, cefquinome, enrofloxacin and florfenicol may be appropriate for the treatment of mastitis infections caused by susceptible Arcobacter spp. in buffalos.en_US
dc.identifier.citationAltan, F. ve Alp, S. Y. (2022). Antimicrobial susceptibility testing of Arcobacter butzleri and Arcobacter cryaerophilus isolated from buffalo milk with subclinical mastitis: A different approach. Journal of the Hellenic Veterinary Medical Society, 73(2), 4227-4234.en_US
dc.identifier.doi10.12681/jhvms.27186
dc.identifier.endpage4234en_US
dc.identifier.issn1792-2720
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85134411587
dc.identifier.scopusqualityQ4
dc.identifier.startpage4227en_US
dc.identifier.urihttps://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/27186
dc.identifier.urihttps://hdl.handle.net/11468/13632
dc.identifier.volume73en_US
dc.identifier.wosWOS:000825157800041
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorAltan, Feray
dc.institutionauthorAlp, Simten Yeşilmen
dc.language.isoenen_US
dc.publisherHellenic Veterinary Medical Societyen_US
dc.relation.ispartofJournal of the Hellenic Veterinary Medical Society
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectArcobacter spp.en_US
dc.subjectBuffalosen_US
dc.subjectMicen_US
dc.subjectPharmacodynamicen_US
dc.subjectPharmacokineticen_US
dc.titleAntimicrobial susceptibility testing of Arcobacter butzleri and Arcobacter cryaerophilus isolated from buffalo milk with subclinical mastitis: A different approachen_US
dc.titleAntimicrobial susceptibility testing of Arcobacter butzleri and Arcobacter cryaerophilus isolated from buffalo milk with subclinical mastitis: A different approach
dc.typeArticleen_US

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