Relations between mood characteristics, circadian preferences, and functionality in multiple sclerosis

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dc.contributor.authorOzdemir, Pinar G.
dc.contributor.authorMilanlioglu, Aysel
dc.contributor.authorBoysan, Murat
dc.contributor.authorCilingir, Vedat
dc.contributor.authorAydin, Nuri
dc.contributor.authorAtli, Abdullah
dc.date.accessioned2024-04-24T17:20:32Z
dc.date.available2024-04-24T17:20:32Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective. Multiple sclerosis (MS) is a progressive disorder that results in demyelinization of the nerve fibers of the central nervous system. We aimed to determine chronobiological and mood features in patients with MS. Methods. The sample comprised 75 patients with MS (54 women and 21 men) and 50 healthy individuals (38 women and 12 men). Sixty-three patients were relapsing - remitting MS and twelve patients had secondary progressive-type MS. Mood characteristics were assessed using subscales of the Profile of Mood States (POMS). Chronotypical characteristics were determined by the Morningness-Eveningness Questionnaire (MEQ). Univariate and structural equation modeling was applied to untangle the possible connections between variables. Results. Both relapsing - remitting and secondary progressive patients scored higher on the depression - dejection and fatigue - inertia scales of the POMS than healthy individuals. Circadian preferences did not differ significantly between these groups. Patients using glatiramer acetate and other types of drugs had greater severity of functional impairment measured relative to interferon-beta treatment group. Glatiramer acetate had more negative effects on mood than interferon-beta therapy. This finding may be the result of significantly higher duration of disease and higher symptom severity scores in glatiramer acetate group. Conclusions. In the structural equation model, gender was found to be predictive for characteristics of mood.en_US
dc.identifier.doi10.3109/13651501.2014.980831
dc.identifier.endpage154en_US
dc.identifier.issn1365-1501
dc.identifier.issn1471-1788
dc.identifier.issue2en_US
dc.identifier.pmid25363199
dc.identifier.scopus2-s2.0-84929081385
dc.identifier.scopusqualityQ2
dc.identifier.startpage148en_US
dc.identifier.urihttps://doi.org/10.3109/13651501.2014.980831
dc.identifier.urihttps://hdl.handle.net/11468/19112
dc.identifier.volume19en_US
dc.identifier.wosWOS:000354220500012
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofInternational Journal of Psychiatry in Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMultiple Sclerosisen_US
dc.subjectMooden_US
dc.subjectDisabilityen_US
dc.subjectCircadian Preferencesen_US
dc.titleRelations between mood characteristics, circadian preferences, and functionality in multiple sclerosisen_US
dc.titleRelations between mood characteristics, circadian preferences, and functionality in multiple sclerosis
dc.typeArticleen_US

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