Fatty Acid and Essential Oil Compositions of Trifolium angustifolium var. angustifolium with Antioxidant, Anticholinesterase and Antimicrobial Activities

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dc.contributor.authorErtas, Abdulselam
dc.contributor.authorBoga, Mehmet
dc.contributor.authorHasimi, Nesrin
dc.contributor.authorYilmaz, Mustafa Abdullah
dc.date.accessioned2024-04-24T17:34:00Z
dc.date.available2024-04-24T17:34:00Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractThis study represents the first report on the chemical composition and biological activity of Trifolium angustifolium var. angustifolium. The major components of the essential oil were identified as hexatriacontene (23.0%), arachidic acid (15.5%) and alpha-selinene (10.0%). The main constituents of the fatty acid obtained from the petroleum ether extract were identified as palmitic acid (29.8%), linoleic acid (18.6%) and oleic acid (10.5%). In particular, the water extract exhibited higher activity than alpha-tocopherol and BHT, which were used as standards in the ABTS cation radical scavenging assay and indicated higher inhibitory effect against acetylcholinesterase enzyme than the reference compound, galanthamine but exhibited weak activity in beta-carotene bleaching, DPPH-free radical scavenging, and cupric-reducing antioxidant capacity assays. The petroleum ether extract exhibited higher activity than alpha-tocopherol which was used as standard in the beta-carotene bleaching method at concentration 100 mu g/mL. The acetone extract exhibited higher activity than alpha-tocopherol which was used as standard cupric reducing antioxidant capacity (CUPRAC) method at 100 mu g/mL concentration The acetone and methanol extracts were active on all microorganisms tested with a small zone diameter indicating weak activity.en_US
dc.description.sponsorshipResearch Fund of Dicle University (DUBAP)en_US
dc.description.sponsorshipWe thank the Research Fund of Dicle University (DUBAP) for the partial support of this study. The authors wish to express their gratitude to Dr. Mine Kocyigit for helpful assistance in botanical identification.en_US
dc.identifier.endpage241en_US
dc.identifier.issn1735-0328
dc.identifier.issn1726-6890
dc.identifier.issue1en_US
dc.identifier.pmid25561929
dc.identifier.scopus2-s2.0-84922548787
dc.identifier.scopusqualityQ2
dc.identifier.startpage233en_US
dc.identifier.urihttps://hdl.handle.net/11468/20918
dc.identifier.volume14en_US
dc.identifier.wosWOS:000351641200024
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherShaheed Beheshti Univ, Sch Pharmacyen_US
dc.relation.ispartofIranian Journal of Pharmaceutical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTrifolium Angustifolium Var. Angustifoliumen_US
dc.subjectFatty Aciden_US
dc.subjectEssential Oilen_US
dc.subjectAntioxidanten_US
dc.subjectAntimicrobialen_US
dc.subjectAnticholinesteraseen_US
dc.titleFatty Acid and Essential Oil Compositions of Trifolium angustifolium var. angustifolium with Antioxidant, Anticholinesterase and Antimicrobial Activitiesen_US
dc.titleFatty Acid and Essential Oil Compositions of Trifolium angustifolium var. angustifolium with Antioxidant, Anticholinesterase and Antimicrobial Activities
dc.typeArticleen_US

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