The effect of ACE gene polymorphisms on Doppler blood flow parameters of carotid and brachial arteries in patients with myocardial infarction

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dc.contributor.authorBilici, Aslan
dc.contributor.authorUlgen, Mehmet Siddik
dc.contributor.authorNazaroglu, Hasan
dc.contributor.authorOzturk, Onder
dc.contributor.authorEkici, Faysal
dc.contributor.authorAkgul, Cihan
dc.contributor.authorAlan, Bircan
dc.date.accessioned2024-04-24T17:14:32Z
dc.date.available2024-04-24T17:14:32Z
dc.date.issued2006
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe authors investigated the relationship between the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and the blood flow characteristics of common carotid (CCA) and brachial arteries (BA) by color Doppler ultrasound (CDUS) in patients with acute anterior myocardial infarction (AAMI). Sixty four patients (11 women and 53 men), aged 25 to 77 years, with AAMI were studied. The ACE genotypes were established. Peak-systolic (PSV) and end-diastolic velocity (EDV) of right and left CCA, PSV of right BA, and intimal-medial thickness (IMT) of both CCAs were measured by CDUS. All results were evaluated statistically. The ACE genotypes were distributed as follows: 43.8% DD, 43.8% ID, and 12.5% II. PSVs of BA and both CCAs were lower in patients with DD and ID than with 11 (p < 0.05). EDVs of both CCAs were also lower in the same groups, but statistically not significant (p > 0.05). IMTs of both CCAs did not differ among patients with various ACE genotypes (p > 0.05). These results suggest that ACE I/D polymorphism influences Doppler blood flow parameters of both BA and CCA, but does not affect IMT of CCA.en_US
dc.identifier.doi10.1177/0003319706295216
dc.identifier.endpage685en_US
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue6en_US
dc.identifier.pmid17235107
dc.identifier.scopus2-s2.0-33845700336
dc.identifier.scopusqualityQ2
dc.identifier.startpage681en_US
dc.identifier.urihttps://doi.org/10.1177/0003319706295216
dc.identifier.urihttps://hdl.handle.net/11468/18032
dc.identifier.volume57en_US
dc.identifier.wosWOS:000243128100002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleThe effect of ACE gene polymorphisms on Doppler blood flow parameters of carotid and brachial arteries in patients with myocardial infarctionen_US
dc.titleThe effect of ACE gene polymorphisms on Doppler blood flow parameters of carotid and brachial arteries in patients with myocardial infarction
dc.typeArticleen_US

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