The importance of hematologic indices in the risk stratification of patients with acute decompensated systolic heart failure

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dc.contributor.authorPolat, Nihat
dc.contributor.authorYildiz, Abdulkadir
dc.contributor.authorBilik, Mehmet Zihni
dc.contributor.authorAydin, Mesut
dc.contributor.authorAcet, Halit
dc.contributor.authorKaya, Hasan
dc.contributor.authorDemir, Muhammed
dc.date.accessioned2024-04-24T17:27:50Z
dc.date.available2024-04-24T17:27:50Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives: In patients with heart failure, a variety of hemogram parameters are known to be of prognostic significance. This study aimed to investigate which of these parameters is/are useful in predicting one-year all-cause mortality in patients with acute decompensated heart failure (ADHF). Study design: Patients who were hospitalized between September 2012-March 2013 in our hospital with systolic-ADHF with ejection fraction <= 40%, symptoms, and findings of congestion were enrolled retrospectively in the study. The study population was divided into two groups based on one-year-mortality. Results: 119 patients with ADHF (mean-age 67 +/- 14 years; 55% male) were enrolled in the study. One-year-mortality occurred in 29% of patients. Hemoglobin levels, platelet, basophil and lymphocyte counts were significantly lower, while red-cell distribution width (RDW) was found to be significantly higher in the one-year-mortality group. Neutrophil, monocyte, and eosinophil counts were similar in the two groups. Furthermore, lower estimated glomerular-filtration-rate (eGFR) and unused angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (ACEI/ARB) were associated with mortality. Age, presence of hypertension, right-ventricular diameter, eGFR, ACE/ARB treatment, hemoglobin levels, RDW and platelet, leukocyte, lymphocyte, basophil, neutrophil, monocyte, and eosinophil-counts were found to have prognostic significance in univariate analysis. In multivariate analysis, decreased platelet, lymphocyte-counts and hemoglobin level on admission and unused ACE/ARB treatment at discharge (p<0.05) were found to be independent factors predicting one-year-mortality. Conclusion: Among hematological indices; hemoglobin level, platelet and lymphocyte counts are readily available, useful and inexpensive markers for the prediction of one-year all-cause mortality in ADHF patients.en_US
dc.identifier.doi10.5543/tkda.2015.76281
dc.identifier.endpage165en_US
dc.identifier.issn1016-5169
dc.identifier.issue2en_US
dc.identifier.pmid25782120
dc.identifier.startpage157en_US
dc.identifier.trdizinid171870
dc.identifier.urihttps://doi.org/10.5543/tkda.2015.76281
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/171870
dc.identifier.urihttps://hdl.handle.net/11468/20214
dc.identifier.volume43en_US
dc.identifier.wosWOS:000421963600005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of The Turkish Society of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBlood Plateletsen_US
dc.subjectHeart Failureen_US
dc.subjectHemoglobinsen_US
dc.subjectMortalityen_US
dc.subjectPredictive Value Of Testsen_US
dc.titleThe importance of hematologic indices in the risk stratification of patients with acute decompensated systolic heart failureen_US
dc.titleThe importance of hematologic indices in the risk stratification of patients with acute decompensated systolic heart failure
dc.typeArticleen_US

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