The role of vitamin B1-B2 and plasma lipid profile in intrahepatic cholestasis of pregnancy

Basit Öğe Kaydı
dc.contributor.authorBasaranoglu, Serdar
dc.contributor.authorAgacayak, Elif
dc.contributor.authorUcmak, Feyzullah
dc.contributor.authorTunc, Senem Yaman
dc.contributor.authorDeregozu, Aysegul
dc.contributor.authorAkkurt, Zeynep Meltem
dc.contributor.authorPeker, Nurullah
dc.date.accessioned2024-04-24T17:18:01Z
dc.date.available2024-04-24T17:18:01Z
dc.date.issued2017
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: The present study aimed to determine the levels of total cholesterol, triglycerides (TG), low-density lipoproteins (LDL), high-density lipoproteins (HDL), and vitamins B1 and B2 in intrahepatic cholestasis of pregnancy (ICP) patients, and to evaluate if these were involved in the pathophysiology of the disease. Methods: The prospective randomized study included 35 pregnant patients who were admitted to the Gynecology and Obstetrics Polyclinic, Faculty of Medicine at Dicle University and who were diagnosed with ICP (Group 1), and 40 healthy pregnant women who were admitted in the same period and who had no systemic diseases that might complicate the pregnancy during the pregnancy follow-up (Group 2). Serum lipid levels and vitamins B1 and B2 were determined and compared, and statistical comparisons of the groups were made. Results: There was no difference between the TG levels of the two groups (P=0.631). Total cholesterol, LDL, HDL, and vitamin B1 and B2 levels were higher in Group 1 than in Group 2 (P=0.001, P=0.001, P=0.001, P=0.001, and P=0.032, respectively). Conclusions: Increased levels of vitamins B1 and B2 may indicate a need for increased energy metabolism at the fetus. So we believe that new studies are required, which will be supported by the placental analyses of the pyruvate and lactate levels in maternal blood at delivery and fetal cord blood in order to develop a better understanding on the fetal effects of energy metabolism.en_US
dc.identifier.doi10.1515/jpm-2015-0337
dc.identifier.endpage465en_US
dc.identifier.issn0300-5577
dc.identifier.issn1619-3997
dc.identifier.issue4en_US
dc.identifier.pmid27049609
dc.identifier.scopus2-s2.0-85020411144
dc.identifier.scopusqualityQ1
dc.identifier.startpage461en_US
dc.identifier.urihttps://doi.org/10.1515/jpm-2015-0337
dc.identifier.urihttps://hdl.handle.net/11468/18537
dc.identifier.volume45en_US
dc.identifier.wosWOS:000402366100010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofJournal of Perinatal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCholestasisen_US
dc.subjectLipidsen_US
dc.subjectPregnancyen_US
dc.subjectVitamin B1en_US
dc.subjectVitamin B2en_US
dc.titleThe role of vitamin B1-B2 and plasma lipid profile in intrahepatic cholestasis of pregnancyen_US
dc.titleThe role of vitamin B1-B2 and plasma lipid profile in intrahepatic cholestasis of pregnancy
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu