Salutary effects of radiopaque contrast media on the survival of random-pattern skin flaps in the rat

Basit Öğe Kaydı
dc.contributor.authorAşkar, İbrahim
dc.contributor.authorBozkurt, Mehmet
dc.contributor.authorOktay, Mehmet Faruk
dc.contributor.authorGürlek, Ali
dc.contributor.authorKeleş, Celalettin
dc.date.accessioned2024-04-24T15:59:29Z
dc.date.available2024-04-24T15:59:29Z
dc.date.issued2004
dc.departmentDicle Üniversitesi, Tıp Fakülhtesi, Cerrahi Tıp Bilimleri Bölümü, Plastik Cerrahi Ana Bilim Dalıen_US
dc.description.abstractThe radiopaque contrast medium diatrizoate, has a vasodilator effect so that it is used in sudden-deafness secondary ischemic injury. However, ischemic problems are encountered, especially when longer flaps are elevated. A longer flap also has ischemic and relatively ischemic tissue, and may obtain some benefit from contrast media. Forty male Sprague-Dawley rats, weighing about 350-400 g, were used, and randomly divided into four groups (n = 10 rats each group): group 1 was the control, group 2 the diatrizoate, group 3 the iopamidol, and group 4 the iothalamate group. A rectangular 3 x 10 cm caudally based dorsal skin flap was elevated, and sutured back to its original place. In the control group, no pharmacologic agent was administered. Sodium-meglumine-diatrizoate 10 mg/kg/day was administered parenterally in the first experimental group (diatrizoate group); iopamidol 10 mg/kg/day in the second experimental group (iopamidol group); and iothalamate sodium 10 mg/kg/day in the third experimental group (iothalamate group) for 7 postoperative days. On postoperative day 7, all flaps were photographed, and the area of flap survival was measured by using a polar planimeter. The results were statistically evaluated with the Kruskal-Wallis test and Mann-Whitney U-test (P = 0.05). The mean flap survival ranged from 79% in the iopamidol group to 83% in the diatrizoate group, and was significantly greater in all experimental groups (P < 0.05) compared to the control group (59%). There was no significant difference between experimental groups (P < 0.05). We believe that radiopaque contrast media have a beneficial effect in improving skin flap viability when distal flap necrosis is a potential complication of longer flaps.en_US
dc.identifier.citationAşkar, İ., Bozkurt, M., Oktay, M. O., Gürlek, A. ve Keleş, C. (2004). Salutary effects of radiopaque contrast media on the survival of random-pattern skin flaps in the rat: An experimental study. Microsurgery, 24(1), 81-84.
dc.identifier.doi10.1002/micr.10193
dc.identifier.endpage84en_US
dc.identifier.issn0738-1085
dc.identifier.issn1098-2752
dc.identifier.issue1en_US
dc.identifier.pmid14748032
dc.identifier.scopus2-s2.0-0842310841
dc.identifier.scopusqualityQ2
dc.identifier.startpage81en_US
dc.identifier.urihttps://doi.org/10.1002/micr.10193
dc.identifier.urihttps://hdl.handle.net/11468/14093
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/micr.10193
dc.identifier.volume24en_US
dc.identifier.wosWOS:000188956700016
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAşkar, İbrahim
dc.institutionauthorBozkurt, Mehmet
dc.institutionauthorOktay, Mehmet Faruk
dc.institutionauthorKeleş, Celalettin
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofMicrosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleSalutary effects of radiopaque contrast media on the survival of random-pattern skin flaps in the raten_US
dc.titleSalutary effects of radiopaque contrast media on the survival of random-pattern skin flaps in the rat
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Salutary effects of radiopaque contrast media on the survival of random-pattern skin flaps in the rat An experimental study.pdf
Boyut:
142.59 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu