Clinical performance of rheumatoid arthritis impact of disease score: a real-life evidence from the multicenter nationwide registry BioStaR

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dc.contributor.authorMelikoglu, Meltem Alkan
dc.contributor.authorAtaman, Sebnem
dc.contributor.authorBodur, Hatice
dc.contributor.authorCay, Hasan Fatih
dc.contributor.authorCapkin, Erhan
dc.contributor.authorAkgul, Ozgur
dc.contributor.authorCevik, Remzi
dc.date.accessioned2024-04-24T16:00:06Z
dc.date.available2024-04-24T16:00:06Z
dc.date.issued2021
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe rheumatoid arthritis impact of disease (RAID) score was developed as a patient-derived composite response index for the evaluation of the disease impact on cases with rheumatoid arthritis (RA). The aim of this study was to evaluate the psychometric properties and performance of RAID score in the real-life settings. Cases with RA from our multi-center, nationwide registry called Biologic and targeted Synthetic antirheumatic drugs Registry RA (BioStaR RA) were included in this cross-sectional observational study. Demographic data, disease duration, pain, patient's global assessment (PGA) and physician's global assessment (PhyGA) were recorded. DAS28-ESR, DAS28-CRP, the simplified disease activity index (SDAI) and the clinical disease activity index (CDAI) were assessed as disease activity evaluations. The health assessment questionnaire-disability index (HAQ-DI) and RAID were completed by all the participants. The construct validity was tested by the analysis of correlations between RAID score and scores of PGA, disease activity indexes and HAQ-DI. We also evaluated the discriminatory ability of RAID to distinguish patients with different levels of disease activity and disability and the cut-off values were calculated by ROC analysis. 585 cases with RA were included in this investigation. The RAID score was significantly positively correlated with PGA, all disease activity indexes and HAQ-DI (p < 0.001). The discriminatory ability of RAID score in different disease activity and disability groups was also demonstrated (p < 0.001). To estimate DAS28-ESR (remission/low + moderate + high), RAID score cut-off points were 2.88 (sensitivity 73%, specificity 62%), 3.23 (sensitivity 75%, specificity 60%) and 3.79 (sensitivity 74%, specificity 58%), respectively. Our study indicated that RAID was a reliable tool in daily clinical practice by presenting its correlations with disease activity and disability assessments and by showing its discriminatory ability in these parameters in the real-life experiences.en_US
dc.description.sponsorshipTurkish League Against Rheumatism (TLAR) [06.23.2018-16]en_US
dc.description.sponsorshipThis study was funded Turkish League Against Rheumatism (TLAR) (Grant number 06.23.2018-16).en_US
dc.identifier.doi10.1007/s00296-021-04992-3
dc.identifier.endpage1978en_US
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.issue11en_US
dc.identifier.pmid34559275
dc.identifier.scopus2-s2.0-85115610513
dc.identifier.scopusqualityQ1
dc.identifier.startpage1971en_US
dc.identifier.urihttps://doi.org/10.1007/s00296-021-04992-3
dc.identifier.urihttps://hdl.handle.net/11468/14373
dc.identifier.volume41en_US
dc.identifier.wosWOS:000698872100003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofRheumatology International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRheumatoid Arthritisen_US
dc.subjectThe Rheumatoid Arthritis Impact Of Disease (Raid)en_US
dc.subjectConstruct Validityen_US
dc.subjectDiscriminatory Abilityen_US
dc.titleClinical performance of rheumatoid arthritis impact of disease score: a real-life evidence from the multicenter nationwide registry BioStaRen_US
dc.titleClinical performance of rheumatoid arthritis impact of disease score: a real-life evidence from the multicenter nationwide registry BioStaR
dc.typeArticleen_US

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