The fate of neurotization techniques on reinnervation after denervation of the gastrocnemius muscle: An experimental study

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dc.contributor.authorAskar, I
dc.contributor.authorSabuncuoglu, BT
dc.contributor.authorYormuk, E
dc.contributor.authorSaray, A
dc.date.accessioned2024-04-24T16:24:10Z
dc.date.available2024-04-24T16:24:10Z
dc.date.issued2001
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn nerve injuries, if it is not possible to reinnervate muscle by using neurorrhaphy and nerve grafting technique, reinnervation should be provided by the use of neuroization-directly implanting motor nerve into muscle. A comparative study of three techniques of neurotization is presented in rabbits. In this experimental study, a total of 40 white New Zealand rabbits were used and divided into four groups, each including 10 rabbits. In the first group (control-Group 1), only surgical exposure of the gastrocnemius muscle, main muscle nerve (tibial nerve), and peroneal nerve was done, without any injury to the nerves. In the second group (direct neurotization group-Group 2), the tibial nerve was transected, and the peroneal nerve, which had already been divided into fascicles, was implanted into the lateral head of the gastrocnemius muscle aneural zone. In the third group (dual neurotization group-Group 3), the tibial nerve which had been transected and re-anastomosed, and the peroneal nerve were implanted into the lateral head of the gastrocnemius muscle. In the last experimental group (hyperneurotization group-Group 4), fascicles of the peroneal nerve were implanted into the lateral head of the gastrocnemius, preserving the tibial nerve. Six months later, changes in the histologic pattern and the functional recovery of the gastrocnemius muscle were investigated. It was found that functional recovery was achieved in all neurotization groups. Groups with the tibial nerve transected had less muscular weights than those of groups with the tibial nerve intact. EMG recordings showed that polyphasic and late potentials were frequently seen in groups with the tibial nerve transected. Degeneration and regeneration of myofibrils was observed in such groups as well. New motor end-plates, including vesicles, were formed in a scattered manner in all neurotization groups. As a result, the authors conclude that direct and dual neurotization techniques are useful in peripheral nerve injuries, if it is not possible to reinnervate muscle by using neurorraphy and nerve grafting, and that there is no suggested superiority among these techniques.en_US
dc.identifier.doi10.1055/s-2001-16027
dc.identifier.endpage355en_US
dc.identifier.issn0743-684X
dc.identifier.issue5en_US
dc.identifier.pmid11499469
dc.identifier.scopus2-s2.0-0034913088
dc.identifier.scopusqualityQ1
dc.identifier.startpage347en_US
dc.identifier.urihttps://doi.org/10.1055/s-2001-16027
dc.identifier.urihttps://hdl.handle.net/11468/16546
dc.identifier.volume17en_US
dc.identifier.wosWOS:000169927500006
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherThieme Medical Publ Incen_US
dc.relation.ispartofJournal of Reconstructive Microsurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeurotizationen_US
dc.subjectDenervation And Reinnervationen_US
dc.subjectGastronuemius Muscleen_US
dc.subjectExperimentalen_US
dc.titleThe fate of neurotization techniques on reinnervation after denervation of the gastrocnemius muscle: An experimental studyen_US
dc.titleThe fate of neurotization techniques on reinnervation after denervation of the gastrocnemius muscle: An experimental study
dc.typeArticleen_US

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