Serum ischaemia-modified albumin level is an irrelevant predictive factor for ischaemic duration in mesenteric ischaemia

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dc.contributor.authorCaliskan, A.
dc.contributor.authorYavuz, C.
dc.contributor.authorKarahan, O.
dc.contributor.authorDemirtas, Sinan
dc.contributor.authorYazici, S.
dc.contributor.authorGuclu, O.
dc.contributor.authorMavitas, B.
dc.date.accessioned2024-04-24T17:14:33Z
dc.date.available2024-04-24T17:14:33Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Acute mesenteric ischaemia is an emergency condition that requires urgent and expeditious diagnosis and immediate surgical or medical intervention. The initial hours are critical for the recovery of the affected bowel segment. Thus, its clinic diagnostic biomarkers are important when it comes to reducing mortality and morbidity rates. Methods: Twenty-four male Sprague-Dawley rats were included in the study. The rats were divided into three equal groups.Those in Group I were sacrificed to determine the basal serum values of ischaemia-modified albumin (IMA) after a simple laparotomy.The superior mesenteric artery (SMA) was clamped in a simple laparotomy in Groups II and III; blood samples were taken at 120 minutes in Group II and 360 minutes in Group III.The serum IMA levels were identified from the blood samples and the results obtained were compared statistically. Results:The serum IMA levels were determined to be 22 +/- 6 (22) mu/L, 34 +/- 7 (34) mu/L and 36 +/- 4 (37) mu/L in Groups I, II and III, respectively.The differences between the groups were not statistically significant. Conclusion: Our results showed that the serum IMA level is not an appropriate biomarker for acute mesenteric ischaemia. Additionally, the IMA level is not an appropriate biomarker for the detection of ischaemia duration. However, future studies should be conducted to clarify the efficacy of serum IMA levels under different ischaemic conditions.en_US
dc.identifier.doi10.1177/0267659113505640
dc.identifier.endpage230en_US
dc.identifier.issn0267-6591
dc.identifier.issn1477-111X
dc.identifier.issue3en_US
dc.identifier.pmid24026108
dc.identifier.scopus2-s2.0-84899051530
dc.identifier.scopusqualityQ1
dc.identifier.startpage226en_US
dc.identifier.urihttps://doi.org/10.1177/0267659113505640
dc.identifier.urihttps://hdl.handle.net/11468/18057
dc.identifier.volume29en_US
dc.identifier.wosWOS:000336186600006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofPerfusion-Uk
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Mesenteric Ischaemiaen_US
dc.subjectDiagnosisen_US
dc.subjectBiomarkeren_US
dc.subjectIschaemia Modified Albuminen_US
dc.subjectMuscle Structuresen_US
dc.titleSerum ischaemia-modified albumin level is an irrelevant predictive factor for ischaemic duration in mesenteric ischaemiaen_US
dc.titleSerum ischaemia-modified albumin level is an irrelevant predictive factor for ischaemic duration in mesenteric ischaemia
dc.typeArticleen_US

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