Mean platelet volume in functional and thrombotic prosthetic mitral valve

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dc.contributor.authorTekbas, Ebru
dc.contributor.authorAkdemir, Ilyas
dc.contributor.authorSoydinc, Serdar
dc.contributor.authorAlici, Hayri
dc.contributor.authorYavuz, Fethi
dc.contributor.authorYuce, Murat
dc.contributor.authorCakici, Musa
dc.date.accessioned2024-04-24T17:08:19Z
dc.date.available2024-04-24T17:08:19Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe mean platelet volume (MPV) values reflect platelet size and are accepted as marker of platelet activation. We sought to test the hypothesis that platelet activation occurs independently from presence or absence of thrombus in prosthetic mitral valve. A total of 168 patients were included in the study. Study participants were divided in three groups: group 1 (n=62) - patients with normal prosthetic mitral valve; group 2 (n=37) - patients with prosthetic mitral valve thrombosis; and group 3 (n=69) - healthy individuals. MPV values were significantly higher in normal and thrombotic prosthetic mitral valve patients than in healthy individuals (P=0.008 and P=0.01, respectively). MPV values were not different between normal prosthetic mitral valve and thrombotic prosthetic mitral valve. This is the first study indicating that increased MPV is present in normal and thrombotic prosthetic mitral valve, implying that platelet reactivity occurs in prosthetic mitral valve irrespective of development of thrombus formation. Blood Coagul Fibrinolysis 23:91-93 (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.en_US
dc.identifier.doi10.1097/MBC.0b013e32834b827c
dc.identifier.endpage93en_US
dc.identifier.issn0957-5235
dc.identifier.issn1473-5733
dc.identifier.issue1en_US
dc.identifier.pmid22024793en_US
dc.identifier.scopus2-s2.0-84855189175en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage91en_US
dc.identifier.urihttps://doi.org/10.1097/MBC.0b013e32834b827c
dc.identifier.urihttps://hdl.handle.net/11468/17298
dc.identifier.volume23en_US
dc.identifier.wosWOS:000298627400017
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofBlood Coagulation & Fibrinolysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectPlatelet Activationen_US
dc.subjectProsthetic Mitral Valveen_US
dc.subjectThrombusen_US
dc.titleMean platelet volume in functional and thrombotic prosthetic mitral valveen_US
dc.typeArticleen_US

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