Comparison of Effects of Pulsed Electromagnetic Field Stimulation on Platelet-Rich Plasma and Bone Marrow Stromal Stem Cell Using Rat Zygomatic Bone Defect Model

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dc.contributor.authorKapi, Emin
dc.contributor.authorBozkurt, Mehmet
dc.contributor.authorSelcuk, Caferi Tayyar
dc.contributor.authorCelik, Mehmet Salih
dc.contributor.authorAkpolat, Veysi
dc.contributor.authorIsik, Fatma Birgul
dc.contributor.authorBozarslan, Beri Hocaoglu
dc.date.accessioned2024-04-24T17:08:26Z
dc.date.available2024-04-24T17:08:26Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground Reconstruction of bone defects that occur because of certain reasons has an important place in plastic and reconstructive surgery. The objective of the treatments of these defects was to reinstate the continuity of tissues placed in the area in which the defect has occurred. In this experimental study, the effect of pulsed electromagnetic field stimulation on platelet-rich plasma (PRP) and bone marrow stromal cell, which propounded that they have positive impact on bone regeneration, was evaluated with the bone healing rate in the zygomatic bone defect model enwrapped with superficial temporal fascia. Methods After creating a 4-mm defect on the zygomatic bone of the experiments, the defect was encompassed with a superficial temporal fascial flap and a nonunion model was created. After surgery, different combinations of the PRP, bone marrow stromal cell, and electromagnetic field applications were implemented on the defective area. All the experiments were subjected to bone density measurement. Results The result revealed that the PRP and pulsed electromagnetic field implementation were rather a beneficial and an effective combination in terms of bone regeneration. Conclusions It was observed that the superficial temporal fascial flap used in the experiment was a good scaffold choice, providing an ideal bone regeneration area because of its autogenous, vascular, and 3-dimensional structures. As a result, it is presumed that this combination in the nonhealing bone defects is a rather useful treatment choice and can be used in a reliable way in clinical applications.en_US
dc.description.sponsorshipDicle University Commission for Scientific Research [Dicle Universitesi Bilimsel Arastirma Komisyonu (DUBAP)]en_US
dc.description.sponsorshipSupported by the Dicle University Commission for Scientific Research [Dicle Universitesi Bilimsel Arastirma Komisyonu (DUBAP)].en_US
dc.identifier.doi10.1097/SAP.0000000000000160
dc.identifier.endpage571en_US
dc.identifier.issn0148-7043
dc.identifier.issn1536-3708
dc.identifier.issue5en_US
dc.identifier.pmid26461101
dc.identifier.scopus2-s2.0-84944405897
dc.identifier.scopusqualityQ2
dc.identifier.startpage565en_US
dc.identifier.urihttps://doi.org/10.1097/SAP.0000000000000160
dc.identifier.urihttps://hdl.handle.net/11468/17343
dc.identifier.volume75en_US
dc.identifier.wosWOS:000363321600018
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofAnnals of Plastic Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBone Defecten_US
dc.subjectPlatelet-Rich Plasmaen_US
dc.subjectMesenchymal Stem Cellen_US
dc.subjectPulsed Electromagnetic Fielden_US
dc.subjectTissue Engineeringen_US
dc.titleComparison of Effects of Pulsed Electromagnetic Field Stimulation on Platelet-Rich Plasma and Bone Marrow Stromal Stem Cell Using Rat Zygomatic Bone Defect Modelen_US
dc.titleComparison of Effects of Pulsed Electromagnetic Field Stimulation on Platelet-Rich Plasma and Bone Marrow Stromal Stem Cell Using Rat Zygomatic Bone Defect Model
dc.typeArticleen_US

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