In vitro NMR proton T-1 measurements in peritoneal ascites

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dc.contributor.authorYilmaz, A
dc.contributor.authorTez, M
dc.contributor.authorGoral, V
dc.contributor.authorBoylu, S
dc.contributor.authorKaplan, A
dc.contributor.authorKavak, G
dc.date.accessioned2024-04-24T17:07:58Z
dc.date.available2024-04-24T17:07:58Z
dc.date.issued1996
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe proton spin-lattice relaxation rate (1/T-1) in malignant and non-malignant ascites was measured with an FT NMR spectrometer operating at 60 MHz. The mean relaxation rate in non-malignant ascites was significantly smaller than that of malignant ascites. However, the 1/T-1 of malignant ascites overlaps with that of non-malignant ascites over all concentrations of total protein (TP) in samples. The 1/T-1 in non-malignant ascites correlates strongly with TP, whilst the 1/T-1 in malignant ascites shows only a moderate correlation. T-1 measurements before and after addition of ascorbic acid (reductant) suggest that there is a small paramagnetic contribution of ions to the 1/T-1 in malignant ascites. The least-squares fitting of 1/T-1 versus TP for non-malignant data gives a linear relationship, and suggests that the T-1 mechanism in non-malignant ascites is caused by a fast chemical exchange of water molecules between protein-bound water and free water.en_US
dc.identifier.doi10.1088/0031-9155/41/3/014
dc.identifier.endpage549en_US
dc.identifier.issn0031-9155
dc.identifier.issue3en_US
dc.identifier.pmid8778831
dc.identifier.scopus2-s2.0-0029873849
dc.identifier.scopusqualityQ1
dc.identifier.startpage539en_US
dc.identifier.urihttps://doi.org/10.1088/0031-9155/41/3/014
dc.identifier.urihttps://hdl.handle.net/11468/17131
dc.identifier.volume41en_US
dc.identifier.wosWOS:A1996TZ46900014
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherIop Publishing Ltden_US
dc.relation.ispartofPhysics in Medicine and Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleIn vitro NMR proton T-1 measurements in peritoneal ascitesen_US
dc.titleIn vitro NMR proton T-1 measurements in peritoneal ascites
dc.typeArticleen_US

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