Clinical significance of procalcitonin in cervico-vaginal secretions of women with preterm rupture of membranes

dc.contributor.authorKuyumcuoglu, U.
dc.contributor.authorKangal, K.
dc.contributor.authorGuzel, A. I.
dc.contributor.authorCelik, Y.
dc.date.accessioned2024-04-24T17:33:21Z
dc.date.available2024-04-24T17:33:21Z
dc.date.issued2010
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: To compare vaginal fluid procalcitonin (PCT) concentrations in cases of preterm premature rupture of membranes (PPROM) and healthy pregnant women, and to determine whether the PCT concentrations are of value in the diagnosis of PPROM cases and clinical amnionitis. Methods: 50 cases with PPROM and 50 healthy pregnant women were enrolled in the study. In the PPROM group, analysis was conducted on PCT concentrations with reference to serum leucocytosis, serum C-reactive protein level and urine analysis, as well as to presence/absence of clinical amnionitis. Statistical analyses were carried out by using the statistical packages for SPSS 12.0 for Windows (SPSS Inc., Chicago, IL, USA). Results: Procalcitonin levels in the PPROM group were significantly higher than in cases of healthy pregnant women (1.17 vs 0.05 ng/ml; p < 0.001). In the PPROM group PCT concentrations between the patients with and without clinical amnionitis were comparable. Also, a significant correlation was observed between PCT and leucocytosis (r = 0.64; p < 0.001) and C-reactive protein (r = 0.90; p < 0.001). Conclusion: These findings suggest that the value of vaginal fluid PCT determinations can be useful for diagnostics of PPROM cases suspected of intrauterine infection.en_US
dc.identifier.endpage321en_US
dc.identifier.issn0390-6663
dc.identifier.issue4en_US
dc.identifier.pmid21355467
dc.identifier.scopus2-s2.0-78650279602
dc.identifier.scopusqualityQ4
dc.identifier.startpage319en_US
dc.identifier.urihttps://hdl.handle.net/11468/20635
dc.identifier.volume37en_US
dc.identifier.wosWOS:000284748100019
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherI R O G Canada, Incen_US
dc.relation.ispartofClinical and Experimental Obstetrics & Gynecology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPremature Rupture Of Membranesen_US
dc.subjectProcalcitoninen_US
dc.subjectC-Reactive Proteinen_US
dc.titleClinical significance of procalcitonin in cervico-vaginal secretions of women with preterm rupture of membranesen_US
dc.titleClinical significance of procalcitonin in cervico-vaginal secretions of women with preterm rupture of membranes
dc.typeArticleen_US

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