Etiological factors and histopathological features in erythema nodosum: A 6-year retrospective cross-sectional study

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dc.authorid0000-0002-0645-8755en_US
dc.contributor.authorSinger, Ralfi
dc.contributor.authorÖzekinci, Selver
dc.date.accessioned2023-10-20T11:30:03Z
dc.date.available2023-10-20T11:30:03Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalıen_US
dc.description.abstractIntroduction: Erythema nodosum (EN) is the most common type of panniculitis. The most frequent etiological factors are streptococcal pharyngitis, sarcoidosis, Behçet’s disease, and tuberculosis. Our objective was to identify the etiological factors and to evaluate the patients’ clinical, laboratory, and histopathological findings. Methods: Eighty-eight patients diagnosed with EN at our clinic between 2013 and 2019 were evaluated retrospectively. Sixty-five patients were evaluated histopathologically. Results: The patients’ ages ranged between 17 and 76 (mean age: 41.91 ± 13.07 years). EN was 7.8 times more frequent in women. Patients presenting with idiopathic EN were significantly older than secondary cases (p < 0.05). Sixty-one patients (69.3%) had an underlying disease (secondary EN). The most common etiological factors were upper respiratory tract infections (n = 26), followed by Behçet’s disease (n = 20). Septal panniculitis was present in 89.2% of cases evaluated histopathologically. Mixed or lobular panniculitis was present in 35.7% of Behçet’s disease patients with EN-like lesions. Vasculitis was also noted in 35.7% of Behçet’s disease patients. Conclusions: Our data confirm the predominance of upper respiratory tract infections and Behçet’s disease among patients with EN in Turkey. Behçet’s disease patients presenting with EN-like lesions may show mixed panniculitis and vasculitis, whereas classic EN patients predominantly show septal panniculitis.en_US
dc.identifier.citationSinger, R. ve Özekinci, S. (2021). Etiological factors and histopathological features in erythema nodosum: A 6-year retrospective cross-sectional study. Acta Dermatovenerologica Alpina, Pannonica et Adriatica, 30(2), 57-61.en_US
dc.identifier.doi10.15570/ACTAAPA.2021.14
dc.identifier.endpage61en_US
dc.identifier.issn1318-4458
dc.identifier.issue2en_US
dc.identifier.pmid34169700
dc.identifier.scopus2-s2.0-85109371954
dc.identifier.scopusqualityQ3
dc.identifier.startpage57en_US
dc.identifier.urihttps://acta-apa.mf.uni-lj.si/journals/acta-dermatovenerol-apa/papers/10.15570/actaapa.2021.14/actaapa.2021.14.pdf
dc.identifier.urihttps://hdl.handle.net/11468/12897
dc.identifier.volume30en_US
dc.identifier.wosWOS:000667743400002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzekinci, Selver
dc.language.isoenen_US
dc.publisherSlovene Medical Societyen_US
dc.relation.ispartofActa Dermatovenerologica Alpina, Pannonica et Adriatica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpidemiologyen_US
dc.subjectErythema nodosumen_US
dc.subjectEtiologyen_US
dc.subjectHistopathological featuresen_US
dc.subjectPanniculitisen_US
dc.titleEtiological factors and histopathological features in erythema nodosum: A 6-year retrospective cross-sectional studyen_US
dc.titleEtiological factors and histopathological features in erythema nodosum: A 6-year retrospective cross-sectional study
dc.typeArticleen_US

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