Baseline Characteristics and Clinical Insights from the ARTEMIS Registry: A Comprehensive Study of Peripartum Cardiomyopathy in Turkiye

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dc.authoridyalim, zafer/0000-0001-7736-0205
dc.contributor.authorKayikcioglu, Meral
dc.contributor.authorBiteker, Murat
dc.contributor.authorMutluer, Ferit Onur
dc.contributor.authorGuzel, Tuncay
dc.contributor.authorYilmaz, Emre
dc.contributor.authorDemir, Emre
dc.contributor.authorNalbantgil, Sanem
dc.date.accessioned2025-02-22T14:08:36Z
dc.date.available2025-02-22T14:08:36Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Peripartum Cardiomyopathy (PPCM) is a life-threatening, rare disorder that occurs during the late stages of pregnancy or the early postpartum period. The ARTEMIS (A RegisTry of pEripartuM cardIomyopathy in Turkish patientS) aims to investigate the clinical characteristics and outcomes of PPCM in Turkiye, providing insights into its management within this specific population. Methods: The ARTEMIS registry retrospectively enrolled patients diagnosed with PPCM within the last five years at 44 cardiology centers across Turkiye. Eligible participants were women over 18 years old, diagnosed with PPCM and without other known cardiac pathology. Data collected included demographic information, clinical presentation, diagnostic modalities, treatment regimens, and outcomes. Results: The study included 293 patients, predominantly between 25 and 35 years old. The majority presented with symptoms such as dyspnea and palpitations, diagnosed postpartum via echocardiography. A low use of advanced diagnostic imaging was noted, relying primarily on echocardiography for evaluation. Common treatments included beta blockers (97.8%), angiotensin-converting enzyme (ACE) inhibitors (71.3%), and in severe cases, bromocriptine (6.9%). The study highlighted a mortality rate of 5.1%, with surviving patients often requiring continued management for heart failure. Diagnostic challenges and variations in treatment responses were noted, reflecting the complexity of PPCM diagnosis and care. Conclusion: The ARTEMIS registry provides valuable insights into the management of PPCM in Turkiye, highlighting the need for targeted educational programs for healthcare providers and patients. It also underscores the importance of national registries in understanding and improving outcomes for rare diseases like PPCM.en_US
dc.description.sponsorshipTurkish Society of Cardiologyen_US
dc.description.sponsorshipThis investigator-initiated registry was endorsed and supported by the Turkish Society of Cardiology. CRO activities were conducted by NER Medical Research Consulting.en_US
dc.identifier.doi10.5543/tkda.2024.63367
dc.identifier.endpage483en_US
dc.identifier.issn1016-5169
dc.identifier.issn1308-4488
dc.identifier.issue7en_US
dc.identifier.pmid39397413en_US
dc.identifier.scopus2-s2.0-85206280473en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage474en_US
dc.identifier.urihttps://doi.org/10.5543/tkda.2024.63367
dc.identifier.urihttps://hdl.handle.net/11468/29500
dc.identifier.volume52en_US
dc.identifier.wosWOS:001355541100001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectB-type natriuretic peptideen_US
dc.subjectcardiomyopathyen_US
dc.subjectdilated cardiomyopathyen_US
dc.subjectechocardiographyen_US
dc.subjectheart failureen_US
dc.subjectpregnancyen_US
dc.subjectTurkiyeen_US
dc.titleBaseline Characteristics and Clinical Insights from the ARTEMIS Registry: A Comprehensive Study of Peripartum Cardiomyopathy in Turkiyeen_US
dc.typeArticleen_US

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