Effects of 2.4 GHz radiofrequency radiation emitted from Wi-Fi equipment on microRNA expression in brain tissue

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dc.contributor.authorDasdag, Suleyman
dc.contributor.authorAkdag, Mehmet Zulkuf
dc.contributor.authorErdal, Mehmet Emin
dc.contributor.authorErdal, Nurten
dc.contributor.authorAy, Ozlem Izci
dc.contributor.authorAy, Mustafa Ertan
dc.contributor.authorYilmaz, Senay Gorucu
dc.date.accessioned2024-04-24T17:20:30Z
dc.date.available2024-04-24T17:20:30Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: MicroRNAs (miRNA) play a paramount role in growth, differentiation, proliferation and cell death by suppressing one or more target genes. However, their interaction with radiofrequencies is still unknown. The aim of this study was to investigate the long-term effects of radiofrequency radiation emitted from a Wireless Fidelity (Wi-Fi) system on some of the miRNA in brain tissue. Materials and methods : The study was carried out on 16 Wistar Albino adult male rats by dividing them into two groups such as sham (n = 8) and exposure (n = 8). Rats in the exposure group were exposed to 2.4 GHz radiofrequency (RF) radiation for 24 hours a day for 12 months (one year). The same procedure was applied to the rats in the sham group except the Wi-Fi system was turned off. Immediately after the last exposure, rats were sacrificed and their brains were removed. miR-9-5p, miR-29a-3p, miR-106b-5p, miR-107, miR-125a-3p in brain were investigated in detail. Results: The results revealed that long-term exposure of 2.4 GHz Wi-Fi radiation can alter expression of some of the miRNAs such as miR-106b-5p (adj p* = 0.010) and miR-107 (adj p* = 0.005). We observed that mir 107 expression is 3.3 times and miR-106b-5p expression is 3.65 times lower in the exposure group than in the control group. However, miR-9-5p, miR-29a-3p and miR-125a-3p levels in brain were not altered. Conclusion: Long-term exposure of 2.4 GHz RF may lead to adverse effects such as neurodegenerative diseases originated from the alteration of some miRNA expression and more studies should be devoted to the effects of RF radiation on miRNA expression levels.en_US
dc.identifier.doi10.3109/09553002.2015.1028599
dc.identifier.endpage561en_US
dc.identifier.issn0955-3002
dc.identifier.issn1362-3095
dc.identifier.issue7en_US
dc.identifier.pmid25775055
dc.identifier.scopus2-s2.0-84940063761
dc.identifier.scopusqualityQ2
dc.identifier.startpage555en_US
dc.identifier.urihttps://doi.org/10.3109/09553002.2015.1028599
dc.identifier.urihttps://hdl.handle.net/11468/19094
dc.identifier.volume91en_US
dc.identifier.wosWOS:000360018700004
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofInternational Journal of Radiation Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject2.4 Ghz Radiofrequencyen_US
dc.subjectWi-Fien_US
dc.subjectMirna In Brainen_US
dc.subjectDiseasesen_US
dc.subjectElectromagnetic Fieldsen_US
dc.titleEffects of 2.4 GHz radiofrequency radiation emitted from Wi-Fi equipment on microRNA expression in brain tissueen_US
dc.titleEffects of 2.4 GHz radiofrequency radiation emitted from Wi-Fi equipment on microRNA expression in brain tissue
dc.typeArticleen_US

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