Which factors may influence the duration of misoprostol-induced abortion in the second trimester?

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dc.contributor.authorSak, M. E.
dc.contributor.authorSoydinc, H. E.
dc.contributor.authorEvsen, M. S.
dc.contributor.authorSak, S.
dc.contributor.authorGul, T.
dc.date.accessioned2024-04-24T17:40:01Z
dc.date.available2024-04-24T17:40:01Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: To investigate the factors that may affect the time interval between induction and fetal expulsion in misoprostol-induced termination of second trimester pregnancy. Materials and Methods: A retrospective analysis of second-trimester pregnancies terminated in the second trimester between October 2008 and 2010 was performed. Induction was done by administration of 400 mcg intravaginal misoprostol. The correlation between the duration of abortion and maternal, fetal, and clinical features were statistically analyzed with multivariate regression analysis. Results: One hundred and seventy-five singleton pregnancies that met the inclusion criteria were evaluated. The average gestational age at the first induction was 18.3 weeks. The mean time interval between the first induction and expulsion was 37.2 +/- 21.3 (range 3 to 160) hours. Fetal expulsion occurred significantly at a later gestational age and those with a higher blood glucose level at admission. However, no correlation could be established between the duration of abortion and the number of pregnancies, deliveries, age, hemoglobin levels or platelet count. Conclusions: Misoprostol is safe and effective in induction of abortion during second-trimester pregnancies. The induction-to-abortion interval is longer in patients with hyperglycemia and advanced gestational age. Prospective, randomized studies are necessary to better understand the factors influencing the duration of abortion.en_US
dc.identifier.endpage358en_US
dc.identifier.issn0390-6663
dc.identifier.issue3en_US
dc.identifier.pmid24283164
dc.identifier.scopus2-s2.0-84885449655
dc.identifier.scopusqualityQ4
dc.identifier.startpage356en_US
dc.identifier.urihttps://hdl.handle.net/11468/21536
dc.identifier.volume40en_US
dc.identifier.wosWOS:000343848400011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherI R O G Canada, Incen_US
dc.relation.ispartofClinical and Experimental Obstetrics & Gynecology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTermination Of Pregnancyen_US
dc.subjectMid-Trimesteren_US
dc.subjectAbortionen_US
dc.subjectMisoprostolen_US
dc.subjectDurationen_US
dc.titleWhich factors may influence the duration of misoprostol-induced abortion in the second trimester?en_US
dc.titleWhich factors may influence the duration of misoprostol-induced abortion in the second trimester?
dc.typeArticleen_US

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