Intracranial hemorrhage: Clinical and demographic features of patients with late hemorrhagic disease

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dc.contributor.authorPirinccioglu, Ayfer Gozu
dc.contributor.authorGurkan, Fuat
dc.contributor.authorBoşnak, Mehmet
dc.contributor.authorAcemoglu, Hamit
dc.contributor.authorDavutoglu, Mehmet
dc.date.accessioned2024-04-24T17:11:33Z
dc.date.available2024-04-24T17:11:33Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: This retrospective study presents clinical, demographical features and radiological findings as well as outcomes of 31 infants with intracranial hemorrhage (ICH) due to vitamin K deficiency and hence evaluates the risk factors involved. Methods: Thirty-one cases (17 males and 14 females) having a mean age of 52.52 +/- 20.80 days with intracranial hemorrhage due to late hemorrhagic disease of the newborn (LHDN), hospitalized in our clinics were included in the study. Cranial computerized tomography (CT) was performed in all patients for the diagnosis and evaluation of ICH. Results: It was found that the most frequent presenting symptoms were pallor (77.4%), seizures (58%), altered consciousness (58%), vomiting (44%) and poor feeding (35%). Pulsatile fontanel was found in 61% and bulging in 26%. Seven (22.5%) patients had prior history of antibiotic usage. All patients (93.5%) except two were breast fed. Sixteen (51.6%) were delivered at home. Eighteen (58%) had a history of single-dose vitamin K prophylaxis on the first day of delivery. Parenchymal (44%), subdural (39%) or subarachnoidal (22.5%) bleeding was observed. Seven (22.6%) were exitus. During the follow-up period (ranging from 3 months to 18 months) neurological examination findings were recorded. Conclusion: Our results indicate that it may be questionable whether single-dose vitamin K prophlaxis at birth is adequate for the prevention of LHDN and if a different timing of this prophylaxis should be made for the exclusively breast fed infants.en_US
dc.identifier.doi10.1111/j.1442-200X.2010.03199.x
dc.identifier.endpage71en_US
dc.identifier.issn1328-8067
dc.identifier.issn1442-200X
dc.identifier.issue1en_US
dc.identifier.pmid20626632
dc.identifier.scopus2-s2.0-79951972814
dc.identifier.scopusqualityQ3
dc.identifier.startpage68en_US
dc.identifier.urihttps://doi.org/10.1111/j.1442-200X.2010.03199.x
dc.identifier.urihttps://hdl.handle.net/11468/17598
dc.identifier.volume53en_US
dc.identifier.wosWOS:000287662900015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPediatrics International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIntracranial Hemorrhageen_US
dc.subjectNewbornen_US
dc.subjectProphylaxisen_US
dc.subjectVitamin K Deficiencyen_US
dc.titleIntracranial hemorrhage: Clinical and demographic features of patients with late hemorrhagic diseaseen_US
dc.titleIntracranial hemorrhage: Clinical and demographic features of patients with late hemorrhagic disease
dc.typeArticleen_US

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