Pregnancy and H1N1 infection in Southeast Turkey

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dc.contributor.authorSoydinc, Hatice Ender
dc.contributor.authorCelen, Mustafa Kemal
dc.contributor.authorYildiz, Bahri
dc.contributor.authorSak, Muhammet Erdal
dc.contributor.authorEvsen, Mehmet Siddik
dc.contributor.authorGul, Talip
dc.date.accessioned2024-04-24T17:20:58Z
dc.date.available2024-04-24T17:20:58Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction: H1N1 Influenza made a great impact a worldwide, as well as in Turkey, in 2009. Clinical experiences have shown that it had a more serious prognosis in pregnant women. In this report, we summarize the cases of 16 pregnant women with H1N1 Influenza. Methodology: The study included 16 pregnant women hospitalized in Dicle University Hospital with complaints of fever, sore throat, cough and myalgia between October and December 2009. The diagnosis of pandemic H1N1 Influenza was confirmed on nasopharyngeal specimens using real-time reverse-transcriptase polymerase chain reaction (RT-PCR) in all patients. Patients who had the same complaints but were not diagnosed as H1N1 Influenza were excluded. The epidemiological, clinical, diagnostic, and outcome features of the patients were recorded. Results: The median age of the patients was 27 years (range 18-41 years). The mean gestational age was 25.4 weeks (range 5-38 weeks). Two cases were twin pregnancy. Two cases had co-morbid diseases including asthma and anemia. The most frequent admission symptoms were fever in 13 cases (81%), cough in 12 cases (75%) and dyspnea in 6 cases (37,5%). Antiviral treatment (oseltamivir 75 mg p.o. bid) was applied in 15 cases. Four cases needed intensive care monitoring and two of them died (12.5%) because of severe respiratory insufficiency. Conclusion: Patients with late gestational age, the presence of co-morbid disease, and multiple pregnancy have poor prognosis. Immediate intervention with antiviral treatment is associated with reduced severity of the disease and duration of hospital stay.en_US
dc.identifier.doi10.3855/jidc.1956
dc.identifier.endpage649en_US
dc.identifier.issn1972-2680
dc.identifier.issue8en_US
dc.identifier.pmid22910572
dc.identifier.scopus2-s2.0-84869074186
dc.identifier.scopusqualityQ2
dc.identifier.startpage644en_US
dc.identifier.urihttps://doi.org/10.3855/jidc.1956
dc.identifier.urihttps://hdl.handle.net/11468/19324
dc.identifier.volume6en_US
dc.identifier.wosWOS:000307718700008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherJ Infection Developing Countriesen_US
dc.relation.ispartofJournal of Infection in Developing Countries
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInfluenza A Virusen_US
dc.subjectH1n1 Subtypeen_US
dc.subjectPregnancyen_US
dc.titlePregnancy and H1N1 infection in Southeast Turkeyen_US
dc.titlePregnancy and H1N1 infection in Southeast Turkey
dc.typeArticleen_US

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