Atherosclerosis and the role of immune cells
dc.contributor.author | Ilhan, Fulya | |
dc.contributor.author | Kalkanli, Sevgi Tas | |
dc.date.accessioned | 2024-04-24T17:15:17Z | |
dc.date.available | 2024-04-24T17:15:17Z | |
dc.date.issued | 2015 | |
dc.department | Dicle Üniversitesi | en_US |
dc.description.abstract | Atherosclerosis is a chronic inflammatory disease arising from lipids, specifically low-density lipoproteins, and leukocytes. Following the activation of endothelium with the expression of adhesion molecules and monocytes, inflammatory cytokines from macrophages, and plasmacytoid dendritic cells, high levels of interferon (IFN)-alpha and beta are generated upon the activation of toll-like receptor-9, and T-cells, especially the ones with Th1 profile, produce pro-inflammatory mediators such as IFN-gamma and upregulate macrophages to adhere to the endothelium and migrate into the intima. This review presents an exhaustive account for the role of immune cells in the atherosclerosis. | en_US |
dc.identifier.doi | 10.12998/wjcc.v3.i4.345 | |
dc.identifier.endpage | 352 | en_US |
dc.identifier.issn | 2307-8960 | |
dc.identifier.issue | 4 | en_US |
dc.identifier.pmid | 25879006 | |
dc.identifier.startpage | 345 | en_US |
dc.identifier.uri | https://doi.org/10.12998/wjcc.v3.i4.345 | |
dc.identifier.uri | https://hdl.handle.net/11468/18402 | |
dc.identifier.volume | 3 | en_US |
dc.identifier.wos | WOS:000417236600003 | |
dc.identifier.wosquality | N/A | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | PubMed | |
dc.language.iso | en | en_US |
dc.publisher | Baishideng Publishing Group Inc | en_US |
dc.relation.ispartof | World Journal of Clinical Cases | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Atherosclerosis | en_US |
dc.subject | Inflammatory Cytokines | en_US |
dc.subject | Pro-Inflammatory Mediators | en_US |
dc.subject | Immune Cells | en_US |
dc.subject | Adhesion Molecules | en_US |
dc.title | Atherosclerosis and the role of immune cells | en_US |
dc.title | Atherosclerosis and the role of immune cells | |
dc.type | Review Article | en_US |