Atherosclerosis and the role of immune cells

dc.contributor.authorIlhan, Fulya
dc.contributor.authorKalkanli, Sevgi Tas
dc.date.accessioned2024-04-24T17:15:17Z
dc.date.available2024-04-24T17:15:17Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractAtherosclerosis is a chronic inflammatory disease arising from lipids, specifically low-density lipoproteins, and leukocytes. Following the activation of endothelium with the expression of adhesion molecules and monocytes, inflammatory cytokines from macrophages, and plasmacytoid dendritic cells, high levels of interferon (IFN)-alpha and beta are generated upon the activation of toll-like receptor-9, and T-cells, especially the ones with Th1 profile, produce pro-inflammatory mediators such as IFN-gamma and upregulate macrophages to adhere to the endothelium and migrate into the intima. This review presents an exhaustive account for the role of immune cells in the atherosclerosis.en_US
dc.identifier.doi10.12998/wjcc.v3.i4.345
dc.identifier.endpage352en_US
dc.identifier.issn2307-8960
dc.identifier.issue4en_US
dc.identifier.pmid25879006
dc.identifier.startpage345en_US
dc.identifier.urihttps://doi.org/10.12998/wjcc.v3.i4.345
dc.identifier.urihttps://hdl.handle.net/11468/18402
dc.identifier.volume3en_US
dc.identifier.wosWOS:000417236600003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherBaishideng Publishing Group Incen_US
dc.relation.ispartofWorld Journal of Clinical Cases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtherosclerosisen_US
dc.subjectInflammatory Cytokinesen_US
dc.subjectPro-Inflammatory Mediatorsen_US
dc.subjectImmune Cellsen_US
dc.subjectAdhesion Moleculesen_US
dc.titleAtherosclerosis and the role of immune cellsen_US
dc.titleAtherosclerosis and the role of immune cells
dc.typeReview Articleen_US

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