Acoustic radiation force impulse (ARFI) elastography for detection of renal damage in children

dc.contributor.authorGoya, Cemil
dc.contributor.authorHamidi, Cihad
dc.contributor.authorEce, Aydin
dc.contributor.authorOkur, Mehmet Hanifi
dc.contributor.authorTasdemir, Bekir
dc.contributor.authorCetincakmak, Mehmet Guli
dc.contributor.authorHattapoglu, Salih
dc.date.accessioned2024-04-24T15:59:55Z
dc.date.available2024-04-24T15:59:55Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractAcoustic radiation force impulse (ARFI) imaging is a promising method for noninvasive evaluation of the renal parenchyma. To investigate the contribution of ARFI quantitative US elastography for the detection of renal damage in kidneys with and without vesicoureteral reflux (VUR). One hundred seventy-six kidneys of 88 children (46 male, 42 female) who had been referred for voiding cystourethrography and 20 healthy controls were prospectively investigated. Patients were assessed according to severity of renal damage on dimercaptosuccinic acid (DMSA) scintigraphy. Ninety-eight age- and gender-matched healthy children constituted the control group. Quantitative shear wave velocity (SWV) measurements were performed in the upper and lower poles and in the interpolar region of each kidney. DMSA scintigraphy was performed in 62 children (124 kidneys). Comparisons of SWV values of kidneys with and without renal damage and/or VUR were done. Significantly higher SWV values were found in non-damaged kidneys. Severely damaged kidneys had the lowest SWV values (P < 0.001). High-grade (grade V-IV) refluxing kidneys had the lowest SWV values, while non-refluxing kidneys had the highest values (P < 0.05). Significant negative correlations were found between the mean quantitative US elastography values and DMSA scarring score (r = -0.788, P < 0.001) and VUR grade (r = -0.634, P < 0.001). SWV values of the control kidneys were significantly higher than those of damaged kidneys (P < 0.05). Our findings suggest decreasing SWV of renal units with increasing grades of vesicoureteric reflux, increasing DMSA-assessed renal damage and decreasing DMSA-assessed differential function.en_US
dc.identifier.doi10.1007/s00247-014-3072-3
dc.identifier.endpage61en_US
dc.identifier.issn0301-0449
dc.identifier.issn1432-1998
dc.identifier.issue1en_US
dc.identifier.pmid25064187
dc.identifier.scopus2-s2.0-84926151264
dc.identifier.scopusqualityQ1
dc.identifier.startpage55en_US
dc.identifier.urihttps://doi.org/10.1007/s00247-014-3072-3
dc.identifier.urihttps://hdl.handle.net/11468/14311
dc.identifier.volume45en_US
dc.identifier.wosWOS:000347165000010
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPediatric Radiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArfi Elastographyen_US
dc.subjectRenal Damageen_US
dc.subjectVesicoureteral Refluxen_US
dc.subjectDmsa Scintigraphyen_US
dc.subjectChilden_US
dc.titleAcoustic radiation force impulse (ARFI) elastography for detection of renal damage in childrenen_US
dc.titleAcoustic radiation force impulse (ARFI) elastography for detection of renal damage in children
dc.typeArticleen_US

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